THI11/YJR156C Protein Information

Standard Name	Thi11p 1
Systematic Name	Yjr156cp
ORF Classification	Verified
Description	Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13 (2)
Name Description	THIamine metabolism

Experimental Data
Molecules/cell	752 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	340
Molecular Weight (Da)	38,631
Isoelectric Point (pI)	7.73

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Thi11p (InterPro)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000136D0A \| P47183 MIPS: YJR156C NCBI: 1015913 \| 1352508 \| 398365659 \| NP_012690.3 GenBank/EMBL/DDBJ: DAA08941.1 \| Z49656

Amino Acid Sequence (or in FASTA format)
1 MSTDKITFLL NWQPTPYHIP IFLAQTKGYF KEQGLDIAIL EPTNPSDVTE 51 LIGSGKVDMG LKAMIHTLAA KARGFPVTSV ASLLDEPFTG VLYLKGSGIT 101 EDFQSLKGKK IGYVGEFGKI QIDELTKHYG MKPEDYTAVR CGMNVAKYII 151 EDKIDAGIGI ECMQQVELEE YLAKQGRPAS DAKMLRIDKL ACLGCCCFCT 201 VLYICNDEFL KKNPEKVRKF LKAIKKATDY VLADPVKAWK EYIDFKPQLN 251 NDLSYKQYQR CYAYFSSSLY NVHRDWKKVT GYGKRLAILP PDYVSNYTNE 301 YLSWPEPEEV SDPLEAQRLM AIHQEKCRQE GTFKRLALPA *

Amino Acid Sequence (or in FASTA format)

       1  MSTDKITFLL NWQPTPYHIP IFLAQTKGYF KEQGLDIAIL EPTNPSDVTE
      51  LIGSGKVDMG LKAMIHTLAA KARGFPVTSV ASLLDEPFTG VLYLKGSGIT
     101  EDFQSLKGKK IGYVGEFGKI QIDELTKHYG MKPEDYTAVR CGMNVAKYII
     151  EDKIDAGIGI ECMQQVELEE YLAKQGRPAS DAKMLRIDKL ACLGCCCFCT
     201  VLYICNDEFL KKNPEKVRKF LKAIKKATDY VLADPVKAWK EYIDFKPQLN
     251  NDLSYKQYQR CYAYFSSSLY NVHRDWKKVT GYGKRLAILP PDYVSNYTNE
     301  YLSWPEPEEV SDPLEAQRLM AIHQEKCRQE GTFKRLALPA *

external links for Thi11p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Thi11p

1)	Hather, R.J. and P.A. Meacock (1996) Characterization of two new thiamine regulated Saccharomyces cerevisiae Genes, THI11 and THI12. Unpublished
2)	Wightman R and Meacock PA (2003) The THI5 gene family of Saccharomyces cerevisiae: distribution of homologues among the hemiascomycetes and functional redundancy in the aerobic biosynthesis of thiamin from pyridoxine. Microbiology 149(Pt 6):1447-60
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41