DAL5/YJR152W Protein Information

Standard Name	Dal5p 1
Systematic Name	Yjr152wp
Alias	Urep1p 2
ORF Classification	Verified
Description	Allantoate permease; ureidosuccinate permease; also transports dipeptides, though with lower affinity than for allantoate and ureidosuccinate; expression is constitutive but sensitive to nitrogen catabolite repression (3, 4, 5)
Name Description	Degradation of Allantoin

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	543
Molecular Weight (Da)	60,849
Isoelectric Point (pI)	8.76

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Dal5p (InterPro)
Transmembrane Domains	There are 12 total predicted transmembrane domains (TMHMM)
Physical Interactions	There are 6 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000128E1F \| P15365 MIPS: YJR152W NCBI: 1015905 \| 118233 \| 295602 \| 398365637 \| NP_012686.3 \| NM_001181810.3 GenBank/EMBL/DDBJ: DAA08937.1 \| M24098 \| Z49652
External Classifications	TC: 2.A.1.14 [The Anion: Cation Symporter (ACS) Family]

Amino Acid Sequence (or in FASTA format)
1 MSADASTNSN ASLDEKNLNI TSEAEIKNED VTAEPVLSTV LSPNGKIVYI 51 SDKVDEAMKL AEEAKEIEVT PEEDRKLRWK IDYCMFPLMC ILYAVQFMDK 101 ISTSSAAVMG LRTDLKMHGD QYSWVTSAFY FGYLFMNLGP VQFIFQRTSH 151 MSKMLAVFIV IWGMLLALHA APTVKYPSFI VLRVLLGCAE SVVTPCFTII 201 TAQYWKTEEQ FTRVSIWFGM NGLGSILINA IAYGVYIHQD SYAIKGWRTL 251 FVITGVITIF IGILIFLWIP DDPSKARFLS KREKLMVVQR IRSNQQGFGN 301 HEIKKYQIIE ALKDVRTWLY FLFTVSSNIP NGGISSFMSI LLNSDFGYSS 351 KETLLMGLPT GAVELVGCPL FGILAVYAAN KKIPFWKYKL SWAIFAAVLA 401 LIASCMLGFA TNSKKARLAG AYLWYISPVS FICVLSNISA NSSGYSKKWT 451 VSSINLVAYA AANLAGPQTF IAKQAPKYHG AKVAMVVCYA VMIVLLSILL 501 IVNLRENKRR DKIAAERGFP EETENLEFSD LTDFENPNFR YTL*

Amino Acid Sequence (or in FASTA format)

       1  MSADASTNSN ASLDEKNLNI TSEAEIKNED VTAEPVLSTV LSPNGKIVYI
      51  SDKVDEAMKL AEEAKEIEVT PEEDRKLRWK IDYCMFPLMC ILYAVQFMDK
     101  ISTSSAAVMG LRTDLKMHGD QYSWVTSAFY FGYLFMNLGP VQFIFQRTSH
     151  MSKMLAVFIV IWGMLLALHA APTVKYPSFI VLRVLLGCAE SVVTPCFTII
     201  TAQYWKTEEQ FTRVSIWFGM NGLGSILINA IAYGVYIHQD SYAIKGWRTL
     251  FVITGVITIF IGILIFLWIP DDPSKARFLS KREKLMVVQR IRSNQQGFGN
     301  HEIKKYQIIE ALKDVRTWLY FLFTVSSNIP NGGISSFMSI LLNSDFGYSS
     351  KETLLMGLPT GAVELVGCPL FGILAVYAAN KKIPFWKYKL SWAIFAAVLA
     401  LIASCMLGFA TNSKKARLAG AYLWYISPVS FICVLSNISA NSSGYSKKWT
     451  VSSINLVAYA AANLAGPQTF IAKQAPKYHG AKVAMVVCYA VMIVLLSILL
     501  IVNLRENKRR DKIAAERGFP EETENLEFSD LTDFENPNFR YTL*

external links for Dal5p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	TCDB
YOGY	DIP	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Dal5p

1)	Chisholm VT, et al. (1987) Regulation of allantoate transport in wild-type and mutant strains of Saccharomyces cerevisiae. J Bacteriol 169(4):1684-90
2)	Drillien R and Lacroute F (1972) Ureidosuccinic acid uptake in yeast and some aspects of its regulation. J Bacteriol 109(1):203-8
3)	Rai R, et al. (1987) Transcriptional regulation of the DAL5 gene in Saccharomyces cerevisiae. J Bacteriol 169(8):3521-4
4)	Turoscy V and Cooper TG (1987) Ureidosuccinate is transported by the allantoate transport system in Saccharomyces cerevisiae. J Bacteriol 169(6):2598-600
5)	Cai H, et al. (2007) Differential Regulation and Substrate Preferences in Two Peptide Transporters of Saccharomyces cerevisiae. Eukaryot Cell 6(10):1805-13