YJR027W Protein Information

Systematic Name	Yjr027wp
Description	Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes (1, 2)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	1,755
Molecular Weight (Da)	198,651
Isoelectric Point (pI)	8.06

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Yjr027wp (InterPro)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000168368 \| P47098 NCBI: 2131097 \| 311033525 \| 6322487 \| 6686356 \| NP_012560.1 GenBank/EMBL/DDBJ: DAA08815.1 \| X87297 \| Z49526
External Classifications	EC: 2.7.7.49 [RNA-directed DNA polymerase] EC: 2.7.7.7 [DNA-directed DNA polymerase] EC: 3.1.26.4 [Ribonuclease H] EC: 3.4.23.- [Aspartic Endopeptidases]

Amino Acid Sequence (or in FASTA format)
1 MESQQLSQHS HISHGSACAS VTSKEVHTNQ DPLDVSASKT EECEKASTKA 51 NSQQTTTPAS SAVPENPHHA SPQPASVPPP QNGPYPQQCM MTQNQANPSG 101 WSFYGHPSMI PYTPYQMSPM YFPPGPQSQF PQYPSSVGTP LSTPSPESGN 151 TFTDSSSADS DMTSTKKYVR PPPMLTSPND FPNWVKTYIK FLQNSNLGGI 201 IPTVNGKPVR QITDDELTFL YNTFQIFAPS QFLPTWVKDI LSVDYTDIMK 251 ILSKSIEKMQ SDTQEANDIV TLANLQYNGS TPADAFETKV TNIIDRLNNN 301 GIHINNKVAC QLIMRGLSGE YKFLRYTRHR HLNMTVAELF LDIHAIYEEQ 351 QGSRNSKPNY RRNLSDEKND SRSYTNTTKP KVIARNPQKT NNSKSKTARA 401 HNVSTSNNSP STDNDSISKS TTEPIQLNNK HDLHLGQELT ESTVNHTNHS 451 DDELPGHLLL DSGASRTLIR SAHHIHSASS NPDINVVDAQ KRNIPINAIG 501 DLQFHFQDNT KTSIKVLHTP NIAYDLLSLN ELAAVDITAC FTKNVLERSD 551 GTVLAPIVQY GDFYWVSKRY LLPSNISVPT INNVHTSEST RKYPYPFIHR 601 MLAHANAQTI RYSLKNNTIT YFNESDVDWS SAIDYQCPDC LIGKSTKHRH 651 IKGSRLKYQN SYEPFQYLHT DIFGPVHNLP KSAPSYFISF TDETTKFRWV 701 YPLHDRREDS ILDVFTTILA FIKNQFQASV LVIQMDRGSE YTNRTLHKFL 751 EKNGITPCYT TTADSRAHGV AERLNRTLLD DCRTQLQCSG LPNHLWFSAI 801 EFSTIVRNSL ASPKSKKSAR QHAGLAGLDI STLLPFGQPV IVNDHNPNSK 851 IHPRGIPGYA LHPSRNSYGY IIYLPSLKKT VDTTNYVILQ GKESRLDQFN 901 YDALTFDEDL NRLTASYQSF IASNEIQESN DLNIESDHDF QSDIELHPEQ 951 PRNVLSKAVS PTDSTPPSTH TEDSKRVSKT NIRAPREVDP NISESNILPS 1001 KKRSSTPQIS NIESTGSGGM HKLNVPLLAP MSQSNTHESS HASKSKDFRH 1051 SDSYSENETN HTNVPISSTG GTNNKTVPQI SDQETEKRII HRSPSIDASP 1101 PENNSSHNIV PIKTPTTVSE QNTEESIIAD LPLPDLPPES PTEFPDPFKE 1151 LPPINSHQTN SSLGGIGDSN AYTTINSKKR SLEDNETEIK VSRDTWNTKN 1201 MRSLEPPRSK KRIHLIAAVK AVKSIKPIRT TLRYDEAITY NKDIKEKEKY 1251 IEAYHKEVNQ LLKMKTWDTD EYYDRKEIDP KRVINSMFIF NKKRDGTHKA 1301 RFVARGDIQH PDTYDTGMQS NTVHHYALMT SLSLALDNNY YITQLDISSA 1351 YLYADIKEEL YIRPPPHLGM NDKLIRLKKS HYGLKQSGAN WYETIKSYLI 1401 KQCGMEEVRG WSCVFKNSQV TICLFVDDMI LFSKDLNANK KIITTLKKQY 1451 DTKIINLGES DNEIQYDILG LEIKYQRGKY MKLGMENSLT EKIPKLNVPL 1501 NPKGRKLSAP GQPGLYIDQD ELEIDEDEYK EKVHEMQKLI GLASYVGYKF 1551 RFDLLYYINT LAQHILFPSR QVLDMTYELI QFMWDTRDKQ LIWHKNKPTE 1601 PDNKLVAISD ASYGNQPYYK SQIGNIFLLN GKVIGGKSTK ASLTCTSTTE 1651 AEIHAISESV PLLNNLSYLI QELNKKPIIK GLLTDSRSTI SIIKSTNEEK 1701 FRNRFFGTKA MRLRDEVSGN NLYVYYIETK KNIADVMTKP LPIKTFKLLT 1751 NKWIH*

Amino Acid Sequence (or in FASTA format)

       1  MESQQLSQHS HISHGSACAS VTSKEVHTNQ DPLDVSASKT EECEKASTKA
      51  NSQQTTTPAS SAVPENPHHA SPQPASVPPP QNGPYPQQCM MTQNQANPSG
     101  WSFYGHPSMI PYTPYQMSPM YFPPGPQSQF PQYPSSVGTP LSTPSPESGN
     151  TFTDSSSADS DMTSTKKYVR PPPMLTSPND FPNWVKTYIK FLQNSNLGGI
     201  IPTVNGKPVR QITDDELTFL YNTFQIFAPS QFLPTWVKDI LSVDYTDIMK
     251  ILSKSIEKMQ SDTQEANDIV TLANLQYNGS TPADAFETKV TNIIDRLNNN
     301  GIHINNKVAC QLIMRGLSGE YKFLRYTRHR HLNMTVAELF LDIHAIYEEQ
     351  QGSRNSKPNY RRNLSDEKND SRSYTNTTKP KVIARNPQKT NNSKSKTARA
     401  HNVSTSNNSP STDNDSISKS TTEPIQLNNK HDLHLGQELT ESTVNHTNHS
     451  DDELPGHLLL DSGASRTLIR SAHHIHSASS NPDINVVDAQ KRNIPINAIG
     501  DLQFHFQDNT KTSIKVLHTP NIAYDLLSLN ELAAVDITAC FTKNVLERSD
     551  GTVLAPIVQY GDFYWVSKRY LLPSNISVPT INNVHTSEST RKYPYPFIHR
     601  MLAHANAQTI RYSLKNNTIT YFNESDVDWS SAIDYQCPDC LIGKSTKHRH
     651  IKGSRLKYQN SYEPFQYLHT DIFGPVHNLP KSAPSYFISF TDETTKFRWV
     701  YPLHDRREDS ILDVFTTILA FIKNQFQASV LVIQMDRGSE YTNRTLHKFL
     751  EKNGITPCYT TTADSRAHGV AERLNRTLLD DCRTQLQCSG LPNHLWFSAI
     801  EFSTIVRNSL ASPKSKKSAR QHAGLAGLDI STLLPFGQPV IVNDHNPNSK
     851  IHPRGIPGYA LHPSRNSYGY IIYLPSLKKT VDTTNYVILQ GKESRLDQFN
     901  YDALTFDEDL NRLTASYQSF IASNEIQESN DLNIESDHDF QSDIELHPEQ
     951  PRNVLSKAVS PTDSTPPSTH TEDSKRVSKT NIRAPREVDP NISESNILPS
    1001  KKRSSTPQIS NIESTGSGGM HKLNVPLLAP MSQSNTHESS HASKSKDFRH
    1051  SDSYSENETN HTNVPISSTG GTNNKTVPQI SDQETEKRII HRSPSIDASP
    1101  PENNSSHNIV PIKTPTTVSE QNTEESIIAD LPLPDLPPES PTEFPDPFKE
    1151  LPPINSHQTN SSLGGIGDSN AYTTINSKKR SLEDNETEIK VSRDTWNTKN
    1201  MRSLEPPRSK KRIHLIAAVK AVKSIKPIRT TLRYDEAITY NKDIKEKEKY
    1251  IEAYHKEVNQ LLKMKTWDTD EYYDRKEIDP KRVINSMFIF NKKRDGTHKA
    1301  RFVARGDIQH PDTYDTGMQS NTVHHYALMT SLSLALDNNY YITQLDISSA
    1351  YLYADIKEEL YIRPPPHLGM NDKLIRLKKS HYGLKQSGAN WYETIKSYLI
    1401  KQCGMEEVRG WSCVFKNSQV TICLFVDDMI LFSKDLNANK KIITTLKKQY
    1451  DTKIINLGES DNEIQYDILG LEIKYQRGKY MKLGMENSLT EKIPKLNVPL
    1501  NPKGRKLSAP GQPGLYIDQD ELEIDEDEYK EKVHEMQKLI GLASYVGYKF
    1551  RFDLLYYINT LAQHILFPSR QVLDMTYELI QFMWDTRDKQ LIWHKNKPTE
    1601  PDNKLVAISD ASYGNQPYYK SQIGNIFLLN GKVIGGKSTK ASLTCTSTTE
    1651  AEIHAISESV PLLNNLSYLI QELNKKPIIK GLLTDSRSTI SIIKSTNEEK
    1701  FRNRFFGTKA MRLRDEVSGN NLYVYYIETK KNIADVMTKP LPIKTFKLLT
    1751  NKWIH*

external links for Yjr027wp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YeastGFP
DIP	Pfam domains
YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Yjr027wp

1)	Kim JM, et al. (1998) Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence. Genome Res 8(5):464-78
2)	Lesage P and Todeschini AL (2005) Happy together: the life and times of Ty retrotransposons and their hosts. Cytogenet Genome Res 110(1-4):70-90