SAG1/YJR004C Protein Information Help

Standard Name Sag1p 1
Systematic Name Yjr004cp
Alias Ag(alpha)1p 1
ORF Classification Verified
Description Alpha-agglutinin of alpha-cells, binds to Aga1p during agglutination, N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin, C-terminal half is highly glycosylated and contains GPI anchor (2, 3, 4)
Name Description Sexual AGglutination 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 650
Molecular Weight (Da) 70,339
Isoelectric Point (pI) 4.22

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Sag1p (InterPro)
Transmembrane Domains There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 3 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001354E0 | P20840
MIPS: YJR004C
NCBI: 1015626 | 1173356 | 171044 | 3353 | 6322463 | 854577 | NP_012537.1 | NM_001181661.1
GenBank/EMBL/DDBJ: DAA08794.1 | M28164 | X16861 | X87611 | Z49504
Amino Acid Sequence (or in FASTA format)
 
       1  MFTFLKIILW LFSLALASAI NINDITFSNL EITPLTANKQ PDQGWTATFD
      51  FSIADASSIR EGDEFTLSMP HVYRIKLLNS SQTATISLAD GTEAFKCYVS
     101  QQAAYLYENT TFTCTAQNDL SSYNTIDGSI TFSLNFSDGG SSYEYELENA
     151  KFFKSGPMLV KLGNQMSDVV NFDPAAFTEN VFHSGRSTGY GSFESYHLGM
     201  YCPNGYFLGG TEKIDYDSSN NNVDLDCSSV QVYSSNDFND WWFPQSYNDT
     251  NADVTCFGSN LWITLDEKLY DGEMLWVNAL QSLPANVNTI DHALEFQYTC
     301  LDTIANTTYA TQFSTTREFI VYQGRNLGTA SAKSSFISTT TTDLTSINTS
     351  AYSTGSISTV ETGNRTTSEV ISHVVTTSTK LSPTATTSLT IAQTSIYSTD
     401  SNITVGTDIH TTSEVISDVE TISRETASTV VAAPTSTTGW TGAMNTYISQ
     451  FTSSSFATIN STPIISSSAV FETSDASIVN VHTENITNTA AVPSEEPTFV
     501  NATRNSLNSF CSSKQPSSPS SYTSSPLVSS LSVSKTLLST SFTPSVPTSN
     551  TYIKTKNTGY FEHTALTTSS VGLNSFSETA VSSQGTKIDT FLVSSLIAYP
     601  SSASGSQLSG IQQNFTSTSL MISTYEGKAS IFFSAELGSI IFLLLSYLLF
     651  *

external links for Sag1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Sag1p
1) Doi S, et al.  (1989) An alpha-specific gene, SAG1 is required for sexual agglutination in Saccharomyces cerevisiae. Curr Genet 15(6):393-8
2) Cappellaro C, et al.  (1994) Mating type-specific cell-cell recognition of Saccharomyces cerevisiae: cell wall attachment and active sites of a- and alpha-agglutinin. EMBO J 13(20):4737-44
3) de Nobel H, et al.  (1995) Genetics of a-agglutunin function in Saccharomyces cerevisiae. Mol Gen Genet 247(4):409-15
4) Zhao H, et al.  (2001) Interaction of alpha-agglutinin and a-agglutinin, Saccharomyces cerevisiae sexual cell adhesion molecules. J Bacteriol 183(9):2874-80