FBP26/YJL155C Protein Information

Standard Name	Fbp26p
Systematic Name	Yjl155cp
ORF Classification	Verified
Description	Fructose-2,6-bisphosphatase, required for glucose metabolism; protein abundance increases in response to DNA replication stress (1, 2)
Name Description	Fructose BisPhosphatase

Experimental Data
Molecules/cell	1680 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	452
Molecular Weight (Da)	52,594
Isoelectric Point (pI)	6.79

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Fbp26p (InterPro)
Physical Interactions	There are 12 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012A3F9 \| P32604 MIPS: YJL155C NCBI: 1015575 \| 1169587 \| 253335 \| 6322306 \| NP_012380.1 GenBank/EMBL/DDBJ: DAA08648.1 \| S42124 \| Z49430
External Classifications	EC: 3.1.3.46 [Fructose-2,6-bisphosphate 2-phosphatase]

Amino Acid Sequence (or in FASTA format)
1 MGYSTISNDN DIKVCVIMVG LPARGKSFIS QKIIRYLSWL SIKAKCFNVG 51 NYRRDVSGNV PMDAEFFNFE NTDNFKLREL AAQNAIKDIV NFFTKEDGSV 101 AVFDATNSTR KRRKWLKDIC EKNNIQPMFL ESWSNDHELI INNAKDIGST 151 SPDYENSEPH VAEADFLERI RQYERFYEPL DPQKDKDMTF IKLVNIIEEV 201 VINKIRTYLE SRIVFYVMNI RPKPKYIWLS RHGESIYNVE KKIGGDSSLS 251 ERGFQYAKKL EQLVKESAGE INLTVWTSTL KRTQQTANYL PYKKLQWKAL 301 DELDAGVCDG MTYEEIEKEY PEDFKARDND KYEYRYRGGE SYRDVVIRLE 351 PVIMELERQE NVLIITHQAV LRCIYAYFMN VPQEESPWMS IPLHTLIKLE 401 PRAYGTKVTK IKANIPAVST YKEKGTSQVG ELSQSSTKLH QLLNDSPLED 451 KF*

Amino Acid Sequence (or in FASTA format)

       1  MGYSTISNDN DIKVCVIMVG LPARGKSFIS QKIIRYLSWL SIKAKCFNVG
      51  NYRRDVSGNV PMDAEFFNFE NTDNFKLREL AAQNAIKDIV NFFTKEDGSV
     101  AVFDATNSTR KRRKWLKDIC EKNNIQPMFL ESWSNDHELI INNAKDIGST
     151  SPDYENSEPH VAEADFLERI RQYERFYEPL DPQKDKDMTF IKLVNIIEEV
     201  VINKIRTYLE SRIVFYVMNI RPKPKYIWLS RHGESIYNVE KKIGGDSSLS
     251  ERGFQYAKKL EQLVKESAGE INLTVWTSTL KRTQQTANYL PYKKLQWKAL
     301  DELDAGVCDG MTYEEIEKEY PEDFKARDND KYEYRYRGGE SYRDVVIRLE
     351  PVIMELERQE NVLIITHQAV LRCIYAYFMN VPQEESPWMS IPLHTLIKLE
     401  PRAYGTKVTK IKANIPAVST YKEKGTSQVG ELSQSSTKLH QLLNDSPLED
     451  KF*

external links for Fbp26p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Fbp26p

1)	Paravicini G and Kretschmer M (1992) The yeast FBP26 gene codes for a fructose-2,6-bisphosphatase. Biochemistry 31(31):7126-33
2)	Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41