GLG2/YJL137C Protein Information

Standard Name	Glg2p
Systematic Name	Yjl137cp
ORF Classification	Verified
Description	Glycogenin glucosyltransferase; self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin; GLG2 has a paralog, GLG1, that arose from the whole genome duplication (1, 2, 3)
Name Description	Glycogenin-Like Gene 2

Experimental Data
Molecules/cell	981 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	380
Molecular Weight (Da)	44,546
Isoelectric Point (pI)	5.96

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Glg2p (InterPro)
Physical Interactions	There are 16 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012B58B \| P47011 MIPS: YJL137C NCBI: 1015542 \| 1217991 \| 1353015 \| 6322324 \| 854560 \| NP_012398.1 GenBank/EMBL/DDBJ: DAA08663.1 \| U25436 \| X87371 \| Z49412

Amino Acid Sequence (or in FASTA format)
1 MAKKVAICTL LYSRDYLPGA LTLAYQLQKL LKHAVVEDEI TLCLLIEKKL 51 FGDEFKPQEI ALIRSLFKEI IIIEPLKDQE KSIEKNKANL ELLKRPELSH 101 TLLKARLWEL VQFDQVLFLD ADTLPLNKEF FEILRLYPEQ TRFQIAAVPD 151 IGWPDMFNTG VLLLIPDLDM ATSLQDFLIK TVSIDGADQG IFNQFFNPIC 201 NYSKEVLHKV SPLMEWIRLP FTYNVTMPNY GYQSSPAMNF FQQHIRLIHF 251 IGTFKPWSRN TTDYDDHYYQ LWRSTQRELY SECHLSNYFT HLQLGNIETE 301 TNFYHEPPCL QDLLNHGKRE NQKHVDLDIT SVDRNASQKS TAEKHDIEKP 351 TSKPQSAFKF DWESTDYLDR VQRAFPKPDT *

Amino Acid Sequence (or in FASTA format)

       1  MAKKVAICTL LYSRDYLPGA LTLAYQLQKL LKHAVVEDEI TLCLLIEKKL
      51  FGDEFKPQEI ALIRSLFKEI IIIEPLKDQE KSIEKNKANL ELLKRPELSH
     101  TLLKARLWEL VQFDQVLFLD ADTLPLNKEF FEILRLYPEQ TRFQIAAVPD
     151  IGWPDMFNTG VLLLIPDLDM ATSLQDFLIK TVSIDGADQG IFNQFFNPIC
     201  NYSKEVLHKV SPLMEWIRLP FTYNVTMPNY GYQSSPAMNF FQQHIRLIHF
     251  IGTFKPWSRN TTDYDDHYYQ LWRSTQRELY SECHLSNYFT HLQLGNIETE
     301  TNFYHEPPCL QDLLNHGKRE NQKHVDLDIT SVDRNASQKS TAEKHDIEKP
     351  TSKPQSAFKF DWESTDYLDR VQRAFPKPDT *

external links for Glg2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Glg2p

1)	Mu J, et al. (1996) Initiation of glycogen synthesis in yeast. Requirement of multiple tyrosine residues for function of the self-glucosylating Glg proteins in vivo. J Biol Chem 271(43):26554-60
2)	Cheng C, et al. (1995) Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae. Mol Cell Biol 15(12):6632-40
3)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41