RPE1/YJL121C Protein Information

Standard Name	Rpe1p 1
Systematic Name	Yjl121cp
Alias	Epi1p , Pos18p 1
ORF Classification	Verified
Description	D-ribulose-5-phosphate 3-epimerase, catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress (1, 2)
Name Description	Ribulose 5-Phosphate Epimerase 1

Experimental Data
Molecules/cell	3310 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	238
Molecular Weight (Da)	25,967
Isoelectric Point (pI)	6.24

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rpe1p (InterPro)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013462D \| P46969 MIPS: YJL121C NCBI: 1008313 \| 1173139 \| 45269607 \| 609674 \| 6322341 \| NP_012414.1 GenBank/EMBL/DDBJ: DAA08681.1 \| AY557858 \| X83571 \| Z49396
External Classifications	EC: 5.1.3.1 [Ribulose-phosphate 3-epimerase]

Amino Acid Sequence (or in FASTA format)
1 MVKPIIAPSI LASDFANLGC ECHKVINAGA DWLHIDVMDG HFVPNITLGQ 51 PIVTSLRRSV PRPGDASNTE KKPTAFFDCH MMVENPEKWV DDFAKCGADQ 101 FTFHYEATQD PLHLVKLIKS KGIKAACAIK PGTSVDVLFE LAPHLDMALV 151 MTVEPGFGGQ KFMEDMMPKV ETLRAKFPHL NIQVDGGLGK ETIPKAAKAG 201 ANVIVAGTSV FTAADPHDVI SFMKEEVSKE LRSRDLLD*

Amino Acid Sequence (or in FASTA format)

       1  MVKPIIAPSI LASDFANLGC ECHKVINAGA DWLHIDVMDG HFVPNITLGQ
      51  PIVTSLRRSV PRPGDASNTE KKPTAFFDCH MMVENPEKWV DDFAKCGADQ
     101  FTFHYEATQD PLHLVKLIKS KGIKAACAIK PGTSVDVLFE LAPHLDMALV
     151  MTVEPGFGGQ KFMEDMMPKV ETLRAKFPHL NIQVDGGLGK ETIPKAAKAG
     201  ANVIVAGTSV FTAADPHDVI SFMKEEVSKE LRSRDLLD*

external links for Rpe1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY

References cited on this page View Complete Literature Guide for Rpe1p

1)	Juhnke H, et al. (1996) Mutants that show increased sensitivity to hydrogen peroxide reveal an important role for the pentose phosphate pathway in protection of yeast against oxidative stress. Mol Gen Genet 252(4):456-64
2)	Miosga T and Zimmermann FK (1996) Cloning and characterization of the first two genes of the non-oxidative part of the Saccharomyces cerevisiae pentose-phosphate pathway. Curr Genet 30(5):404-9
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41