PAM16/YJL104W Protein Information Help

Standard Name Pam16p 1
Systematic Name Yjl104wp
Alias Mia1p , Tim16p
ORF Classification Verified
Description Constituent of the import motor (PAM complex) component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains a J-like domain (1, 2, 3)
Name Description Presequence translocase-Associated Motor 1
Experimental Data
Molecules/cell 3180 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 149
Molecular Weight (Da) 16,216
Isoelectric Point (pI) 10.25

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Pam16p (InterPro)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 77 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013B5E0 | P42949
MIPS: YJL104W
NCBI: 1009450 | 116667387 | 116667389 | 116667391 | 116667393 | 116667395 | 116667397 | 116667399 | 116667401 | 1176485 | 51012665 | 6322357 | 728706 | NP_012431.1
GenBank/EMBL/DDBJ: DAA08696.1 | AY692607 | X85021 | Z49379
Amino Acid Sequence (or in FASTA format)
 
       1  MAHRAFIQVI ITGTQVFGKA FAEAYRQAAS QSVKQGATNA SRRGTGKGEY
      51  GGITLDESCK ILNIEESKGD LNMDKINNRF NYLFEVNDKE KGGSFYLQSK
     101  VYRAAERLKW ELAQREKNAK AKAGDASTAK PPPNSTNSSG ADNSASSNQ*

external links for Pam16p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB GeneMANIA

YOGY


References cited on this page View Complete Literature Guide for Pam16p
1) Frazier AE, et al.  (2004) Pam16 has an essential role in the mitochondrial protein import motor. Nat Struct Mol Biol 11(3):226-33
2) Kozany C, et al.  (2004) The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase. Nat Struct Mol Biol 11(3):234-41
3) Mokranjac D, et al.  (2006) Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor. EMBO J 25(19):4675-85
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41