SAP185/YJL098W Protein Information Help

Standard Name Sap185p 1
Systematic Name Yjl098wp
ORF Classification Verified
Description Protein that forms a complex with the Sit4p protein phosphatase; required for Sit4p function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p; SAP185 has a paralog, SAP190, that arose from the whole genome duplication (1, 2)
Name Description Sit4 Associated Protein 1
Experimental Data
Molecules/cell 11200 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,058
Molecular Weight (Da) 121,401
Isoelectric Point (pI) 4.13

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Sap185p (InterPro)
Physical Interactions There are 96 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052E62 | P40856
MIPS: YJL098W
NCBI: 1008276 | 6322363 | 640005 | 728712 | 731971 | NP_012437.1
GenBank/EMBL/DDBJ: DAA08702.1 | X77923 | X85021 | Z49373
Amino Acid Sequence (or in FASTA format)
 
       1  MSGSFWKFGQ DFGSQSPLAK LLNRAFIKID DKPTSTEAGK IDSNSTDESL
      51  ESNSFKSEDE EEEYELPNRE EDYKAYKPNL SLLNDLLDDE ELYTELMCSN
     101  FKLLVYLKYP EVLSKLIDYV RNSTILESNI DRVTSEDRDL VRGEDKDTTE
     151  DFENAKADKK NIDGTFEEKE RTRSGEEEEL ENEENDSASE DTRVTLPHEL
     201  EEHDDTRRAR IAAEILSADV WPISSALIEN EGLLAKLWSI LRLPSPLSIE
     251  ASTYFMKINE RLLDMNMDGI IEFILKKEHI VDDFLAHIDN PPLMDFLLKV
     301  ISTDKPEISN GVIQLFKKQN LVPKLIHLLD PVFDSCTQSA AGDFLKALVT
     351  ISGNCPNEIT SSIGPNELTR QLVSPNMMKQ LMDIMLKGGN SLNNGVGIII
     401  ELIRKNNSDY DTIQTNYTTI ESHPPTDRDP IYLGYLVKMF SEHMADFNKI
     451  LTEKKIPLLQ TSYGTIEPLG FERFKICELI AELLHCSNMT LLNEPSAYDI
     501  VRERDAERER IFNSQNYVDS NDRSELKENE DDNTGDADDE VEDDTNQVES
     551  ANTSIDGEEV IDKLNSLQIE TNKVNQNMNN EEQHSLMPDF NNGDFKDEED
     601  ENPFEPQYSD VILDSSDIEK NFRVSPNVGD QLKISLQDTR VIDTMLEMFF
     651  HFQWNNFLHN VVYDVVQQIF NGPLKIGYNR FLLDDLLINI RLTDMIINGN
     701  NECIEYEKGH DTRLGYMGHL TLIAEEVTKF TAYIEEMNIT FENTEVMSSL
     751  FESKWIAYTE DVLEDLKEKY NAILGDIAEE GDMLQDEEED AVYDKGERTM
     801  GTVDDYINDI MQMDNVRCQE EEEDEGEGYV SFDEDEPQEY RNGDSVRSKE
     851  SNSSEGKRDQ EQLYYEYVNE DGTKTRLNFN PDSDATEQVP GEVNRDHKIP
     901  LKLKRSFTDA CKSETIPNNT VNAKEESVFQ FSNELSDGWE SSPSNSIPKR
     951  ASPSKNGMNS PMFQHQFELH SPTDEFGGHK DEILSAEGHD YDIDEYDELS
    1001  DDSDEEYDNC EDEDSLDYAD SAAYALCRSK SKDKISWDEE EQARLMGVVK
    1051  FNSEHYRD*

external links for Sap185p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Sap185p
1) Luke MM, et al.  (1996) The SAP, a new family of proteins, associate and function positively with the SIT4 phosphatase. Mol Cell Biol 16(6):2744-55
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41