BBC1/YJL020C Protein Information Help

Standard Name Bbc1p 1
Systematic Name Yjl020cp
Alias Mti1p 2 , Yjl021cp
ORF Classification Verified
Description Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches (2, 3)
Name Description Bni1 synthetic lethal and Bee1 (las17) Complex member 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,157
Molecular Weight (Da) 128,296
Isoelectric Point (pI) 5.06

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Bbc1p (InterPro)
Physical Interactions There are 100 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001267B2 | P47068
MIPS: YJL020C
NCBI: 1006741 | 1006743 | 14627173 | 18033789 | 253722518 | 27808643 | 67463668 | 71041560 | NP_012514.2 | NM_001181454.1
GenBank/EMBL/DDBJ: AAL57239.1 | CAA89311.1 | CAA89312.1 | DAA08776.1 | AF373805 | Z49295 | Z49296
Amino Acid Sequence (or in FASTA format)
       1  MSEPEVPFKV VAQFPYKSDY EDDLNFEKDQ EIIVTSVEDA EWYFGEYQDS
      51  NGDVIEGIFP KSFVAVQGSE VGKEAESSPN TGSTEQRTIQ PEVEQKDLPE
     101  PISPETKKET LSGPVPVPAA TVPVPAATVP VPAATAVSAQ VQHDSSSGNG
     151  ERKVPMDSPK LKARLSMFNQ DITEQVPLPK STHLDLENIP VKKTIVADAP
     201  KYYVPPGIPT NDTSNLERKK SLKENEKKIV PEPINRAQVE SGRIETENDQ
     251  LKKDLPQMSL KERIALLQEQ QRLQAAREEE LLRKKAKLEQ EHERSAVNKN
     301  EPYTETEEAE ENEKTEPKPE FTPETEHNEE PQMELLAHKE ITKTSREADE
     351  GTNDIEKEQF LDEYTKENQK VEESQADEAR GENVAEESEI GYGHEDREGD
     401  NDEEKEEEDS EENRRAALRE RMAKLSGASR FGAPVGFNPF GMASGVGNKP
     451  SEEPKKKQHK EKEEEEPEQL QELPRAIPVM PFVDPSSNPF FRKSNLSEKN
     501  QPTETKTLDP HATTEHEQKQ EHGTHAYHNL AAVDNAHPEY SDHDSDEDTD
     551  DHEFEDANDG LRKHSMVEQA FQIGNNESEN VNSGEKIYPQ EPPISHRTAE
     601  VSHDIENSSQ NTTGNVLPVS SPQTRVARNG SINSLTKSIS GENRRKSINE
     651  YHDTVSTNSS ALTETAQDIS MAAPAAPVLS KVSHPEDKVP PHPVPSAPSA
     701  PPVPSAPSVP SAPPVPPAPP ALSAPSVPPV PPVPPVSSAP PALSAPSIPP
     751  VPPTPPAPPA PPAPLALPKH NEVEEHVKSS APLPPVSEEY HPMPNTAPPL
     801  PRAPPVPPAT FEFDSEPTAT HSHTAPSPPP HQNVTASTPS MMSTQQRVPT
     851  SVLSGAEKES RTLPPHVPSL TNRPVDSFHE SDTTPKVASI RRSTTHDVGE
     901  ISNNVKIEFN AQERWWINKS APPAISNLKL NFLMEIDDHF ISKRLHQKWV
     951  VRDFYFLFEN YSQLRFSLTF NSTSPEKTVT TLQERFPSPV ETQSARILDE
    1001  YAQRFNAKVV EKSHSLINSH IGAKNFVSQI VSEFKDEVIQ PIGARTFGAT
    1051  ILSYKPEEGI EQLMKSLQKI KPGDILVIRK AKFEAHKKIG KNEIINVGMD
    1101  SAAPYSSVVT DYDFTKNKFR VIENHEGKII QNSYKLSHMK SGKLKVFRIV
    1151  ARGYVGW*                                              

external links for Bbc1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) CYC2008 (complexes) MIPS YeastGFP
Candida (CGD) Complexome Pfam domains
YGOB DIP YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Bbc1p
1) Tong AH, et al.  (2002) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science 295(5553):321-4
2) Mochida J, et al.  (2002) The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott-Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae. Genetics 160(3):923-34
3) Tong AH, et al.  (2001) Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294(5550):2364-8
4) Boone C  (2010) Personal Communication to SGD ()