MAL11/YGR289C Protein Information Help

Standard Name Mal11p
Systematic Name Ygr289cp
Alias Agt1p 1
ORF Classification Verified
Description Inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; broad substrate specificity that includes maltotriose; required for isomaltose utilization (1, 2, 3, 4, 5) Also known as: MALT 6
Name Description MALtose fermentation
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 616
Molecular Weight (Da) 67,980
Isoelectric Point (pI) 5.38

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Mal11p (InterPro)
Transmembrane Domains There are 10 total predicted transmembrane domains (TMHMM)
Physical Interactions There are 15 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000125708 | P53048
MIPS: YGR289C
NCBI: 1703215 | 398366431 | 992919 | NP_011805.3 | NM_001181418.3
GenBank/EMBL/DDBJ: DAA08377.1 | L47346 | Z73074
External Classifications TC: 2.A.1.1 [The Sugar Porter (SP) Family]
Amino Acid Sequence (or in FASTA format)
       1  MKNIISLVSK KKAASKNEDK NISESSRDIV NQQEVFNTED FEEGKKDSAF
      51  ELDHLEFTTN SAQLGDSDED NENVINEMNA TDDANEANSE EKSMTLKQAL
     101  LKYPKAALWS ILVSTTLVME GYDTALLSAL YALPVFQRKF GTLNGEGSYE
     151  ITSQWQIGLN MCVLCGEMIG LQITTYMVEF MGNRYTMITA LGLLTAYIFI
     201  LYYCKSLAMI AVGQILSAIP WGCFQSLAVT YASEVCPLAL RYYMTSYSNI
     251  CWLFGQIFAS GIMKNSQENL GNSDLGYKLP FALQWIWPAP LMIGIFFAPE
     301  SPWWLVRKDR VAEARKSLSR ILSGKGAEKD IQVDLTLKQI ELTIEKERLL
     351  ASKSGSFFNC FKGVNGRRTR LACLTWVAQN SSGAVLLGYS TYFFERAGMA
     401  TDKAFTFSLI QYCLGLAGTL CSWVISGRVG RWTILTYGLA FQMVCLFIIG
     451  GMGFGSGSSA SNGAGGLLLA LSFFYNAGIG AVVYCIVAEI PSAELRTKTI
     501  VLARICYNLM AVINAILTPY MLNVSDWNWG AKTGLYWGGF TAVTLAWVII
     551  DLPETTGRTF SEINELFNQG VPARKFASTV VDPFGKGKTQ HDSLADESIS
     601  QSSSIKQREL NAADKC*                                    

external links for Mal11p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS
Aspergillus (AspGD) CYC2008 (complexes) Pfam domains
YGOB Complexome TCDB
YOGY DIP YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Mal11p
1) Han EK, et al.  (1995) Characterization of AGT1 encoding a general alpha-glucoside transporter from Saccharomyces. Mol Microbiol 17(6):1093-107
2) Cheng Q and Michels CA  (1991) MAL11 and MAL61 encode the inducible high-affinity maltose transporter of Saccharomyces cerevisiae. J Bacteriol 173(5):1817-20
3) Charron MJ, et al.  (1986) Structural and functional analysis of the MAL1 locus of Saccharomyces cerevisiae. Mol Cell Biol 6(11):3891-9
4) Alves SL Jr, et al.  (2008) Molecular analysis of maltotriose active transport and fermentation by Saccharomyces cerevisiae reveals a determinant role for the AGT1 permease. Appl Environ Microbiol 74(5):1494-501
5) Teste MA, et al.  (2010) Characterization of a New Multigene Family Encoding Isomaltases in the Yeast Saccharomyces cerevisiae, the IMA Family. J Biol Chem 285(35):26815-24
6) Chow TH, et al.  (1989) Structure of the multigene family of MAL loci in Saccharomyces. Mol Gen Genet 217(1):60-9