BIO2/YGR286C Protein Information Help

Standard Name Bio2p 1
Systematic Name Ygr286cp
ORF Classification Verified
Description Biotin synthase; catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant (1)
Name Description BIOtin 1
Experimental Data
Molecules/cell 504 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 375
Molecular Weight (Da) 41,884
Isoelectric Point (pI) 8.54

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Bio2p (InterPro)
Physical Interactions There are 2 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000126966 | P32451
MIPS: YGR286C
NCBI: 1323523 | 1705465 | 288357 | 6321725 | NP_011802.1 | NM_001181415.1
GenBank/EMBL/DDBJ: CAA51253.1 | CAA97318.1 | DAA08374.1 | X72701 | Z73071
External Classifications EC: 2.8.1.6 [Biotin synthase]
Amino Acid Sequence (or in FASTA format)
       1  MMSTIYRHLS TARPALTKYA TNAAVKSTTA SSEASTLGAL QYALSLDEPS
      51  HSWTKSQLKE IYHTPLLELT HAAQLQHRKW HDPTKVQLCT LMNIKSGGCS
     101  EDCKYCAQSS RNDTGLKAEK MVKVDEVIKE AEEAKRNGST RFCLGAAWRD
     151  MKGRKSAMKR IQEMVTKVND MGLETCVTLG MVDQDQAKQL KDAGLTAYNH
     201  NIDTSREHYS KVITTRTYDD RLQTIKNVQE SGIKACTGGI LGLGESEDDH
     251  IGFIYTLSNM SPHPESLPIN RLVAIKGTPM AEELADPKSK KLQFDEILRT
     301  IATARIVMPK AIIRLAAGRY TMKETEQFVC FMAGCNSIFT GKKMLTTMCN
     351  GWDEDKAMLA KWGLQPMEAF KYDRS*                          

external links for Bio2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
Aspergillus (AspGD) CYC2008 (complexes) MIPS YPL+
Candida (CGD) Complexome Pfam domains YeastGFP
YGOB GeneMANIA YeastRC Structure Prediction (Seattle) YeastRC Public Image Repository
YOGY IMP

References cited on this page View Complete Literature Guide for Bio2p
1) Zhang S, et al.  (1994) The gene for biotin synthase from Saccharomyces cerevisiae: cloning, sequencing, and complementation of Escherichia coli strains lacking biotin synthase. Arch Biochem Biophys 309(1):29-35
2) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41