SCW4/YGR279C Protein Information

Standard Name	Scw4p 1, 2
Systematic Name	Ygr279cp
ORF Classification	Verified
Description	Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating; SCW4 has a paralog, SCW10, that arose from the whole genome duplication (1, 3)
Name Description	Soluble Cell Wall protein 1, 2

Experimental Data
Molecules/cell	6190 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	386
Molecular Weight (Da)	40,173
Isoelectric Point (pI)	4.52

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Scw4p (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 10 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001356B8 \| P53334 MIPS: YGR279C NCBI: 1323509 \| 1723783 \| 6321718 \| NP_011795.1 GenBank/EMBL/DDBJ: DAA08367.1 \| Z73064
External Classifications	EC: 3.2.1.- [Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds]

Amino Acid Sequence (or in FASTA format)
1 MRLSNLIASA SLLSAATLAA PANHEHKDKR AVVTTTVQKQ TTIIVNGAAS 51 TPVAALEENA VVNSAPAAAT STTSSAASVA TAAASSSENN SQVSAAASPA 101 SSSAATSTQS SSSSQASSSS SSGEDVSSFA SGVRGITYTP YESSGACKSA 151 SEVASDLAQL TDFPVIRLYG TDCNQVENVF KAKASNQKVF LGIYYVDQIQ 201 DGVNTIKSAV ESYGSWDDVT TVSIGNELVN GNQATPSQVG QYIDSGRSAL 251 KAAGYTGPVV SVDTFIAVIN NPELCDYSDY MAVNAHAYFD KNTVAQDSGK 301 WLLEQIQRVW TACDGKKNVV ITESGWPSKG ETYGVAVPSK ENQKDAVSAI 351 TSSCGADTFL FTAFNDYWKA DGAYGVEKYW GILSNE*

Amino Acid Sequence (or in FASTA format)

       1  MRLSNLIASA SLLSAATLAA PANHEHKDKR AVVTTTVQKQ TTIIVNGAAS
      51  TPVAALEENA VVNSAPAAAT STTSSAASVA TAAASSSENN SQVSAAASPA
     101  SSSAATSTQS SSSSQASSSS SSGEDVSSFA SGVRGITYTP YESSGACKSA
     151  SEVASDLAQL TDFPVIRLYG TDCNQVENVF KAKASNQKVF LGIYYVDQIQ
     201  DGVNTIKSAV ESYGSWDDVT TVSIGNELVN GNQATPSQVG QYIDSGRSAL
     251  KAAGYTGPVV SVDTFIAVIN NPELCDYSDY MAVNAHAYFD KNTVAQDSGK
     301  WLLEQIQRVW TACDGKKNVV ITESGWPSKG ETYGVAVPSK ENQKDAVSAI
     351  TSSCGADTFL FTAFNDYWKA DGAYGVEKYW GILSNE*

external links for Scw4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Scw4p

1)	Cappellaro C, et al. (1998) New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating. J Bacteriol 180(19):5030-7
2)	Mrsa V, et al. (1997) Specific labelling of cell wall proteins by biotinylation. Identification of four covalently linked O-mannosylated proteins of Saccharomyces cerevisiae. Yeast 13(12):1145-54
3)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41