RTT102/YGR275W Protein Information Help

Standard Name Rtt102p 1
Systematic Name Ygr275wp
ORF Classification Verified
Description Component of both the SWI/SNF and RSC chromatin remodeling complexes; suggested role in chromosome maintenance; possible weak regulator of Ty1 transposition; protein abundance increases in response to DNA replication stress (1, 2, 3, 4)
Name Description Regulator of Ty1 Transposition 1
Experimental Data
Molecules/cell 1550 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 157
Molecular Weight (Da) 17,795
Isoelectric Point (pI) 5.43

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rtt102p (InterPro)
Physical Interactions There are 139 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001D4786 | P53330
MIPS: YGR275W
NCBI: 1323501 | 2104898 | 398366377 | 449802690 | 45270654 | 85697492 | NP_011791.4
GenBank/EMBL/DDBJ: DAA08363.1 | AY558382 | X84098 | Z73060
Amino Acid Sequence (or in FASTA format)
 
       1  MDPQTLITKA NKVSYYGNPT SKESWRYDWY QPSKVSSNVQ QPQQQLGDME
      51  NNLEKYPFRY KTWLRNQEDE KNLQRESCED ILDLKEFDRR ILKKSLMTSH
     101  TKGDTSKATG APSANQGDEA LSVDDIRGAV GNSEAIPGLS AGVNNDNTKE
     151  SKDVKMN*

external links for Rtt102p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains

Complexome


DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Rtt102p
1) Scholes DT, et al.  (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65
2) Baetz KK, et al.  (2004) The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion. Mol Cell Biol 24(3):1232-44
3) Lee KK, et al.  (2004) Proteomic analysis of chromatin-modifying complexes in Saccharomyces cerevisiae identifies novel subunits. Biochem Soc Trans 32(Pt 6):899-903
4) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41