TIM13/YGR181W Protein Information Help

Standard Name Tim13p 1
Systematic Name Ygr181wp
ORF Classification Verified
Description Mitochondrial intermembrane space protein, forms a complex with Tim8p that delivers a subset of hydrophobic proteins to the TIM22 complex for insertion into the inner membrane (1, 2, 3, 4, 5)
Name Description Translocase of the Inner Mitochondrial membrane
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 105
Molecular Weight (Da) 11,286
Isoelectric Point (pI) 8.16

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Tim13p (InterPro)
Physical Interactions There are 18 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000012D5D1 | P53299
MIPS: YGR181W
NCBI: 1323321 | 1430948 | 170785266 | 170785268 | 170785270 | 170785272 | 170785274 | 170785276 | 1723732 | 398366055 | 45270906 | NP_011697.3
GenBank/EMBL/DDBJ: DAA08276.1 | AY558508 | X99074 | Z72966
Amino Acid Sequence (or in FASTA format)
 
       1  MGLSSIFGGG APSQQKEAAT TAKTTPNPIA KELKNQIAQE LAVANATELV
      51  NKISENCFEK CLTSPYATRN DACIDQCLAK YMRSWNVISK AYISRIQNAS
     101  ASGEI*

external links for Tim13p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA


YeastRC Mass Spec (Seattle)

References cited on this page View Complete Literature Guide for Tim13p
1) Koehler CM, et al.  (1999) Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci U S A 96(5):2141-6
2) Leuenberger D, et al.  (1999) Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J 18(17):4816-22
3) Kurz M, et al.  (1999) Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway. Mol Biol Cell 10(7):2461-74
4) Curran SP, et al.  (2002) The role of the Tim8p-Tim13p complex in a conserved import pathway for mitochondrial polytopic inner membrane proteins. J Cell Biol 158(6):1017-27
5) Davis AJ, et al.  (2007) The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein import. Mol Biol Cell 18(2):475-86