GTO1/YGR154C Protein Information

Standard Name	Gto1p 1
Systematic Name	Ygr154cp
ORF Classification	Verified
Description	Omega-class glutathione transferase; induced under oxidative stress; putative peroxisomal localization (1, 2)
Name Description	Glutathione Transferase Omega-like 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	356
Molecular Weight (Da)	41,300
Isoelectric Point (pI)	9.53

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Gto1p (InterPro)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013AF86 \| P48239 MIPS: YGR154C NCBI: 1045259 \| 1323261 \| 1351824 \| 398365927 \| NP_011670.3 GenBank/EMBL/DDBJ: DAA08245.1 \| X85807 \| Z72939
External Classifications	EC: 1.8.5.1 [Glutathione dehydrogenase (ascorbate)] EC: 2.5.1.18 [Glutathione transferase]

Amino Acid Sequence (or in FASTA format)
1 MSVSYKGTIS KTHSVFKPEK GRYYIYGALG CPFTHRAILA RSLKKLEPVL 51 GLVLSHWQLD SKGARFLPAP HRPEKYKERF FTATGGIASA KLDESEELGD 101 VNNDSARLFV DGAFDPVENI SRLSELYYLN DPKYPGTKFT VPVLWDSKTR 151 KIVNNESGDI IRILNSGVFD EFIQSEETNV IDLVPHDLID EIDKNIKWVH 201 PKINLGVYKV GLAENGKIYE TEVKTLFENL QKMECVLKEN YKRLEEQFSG 251 NKQKILAKYF VLGQRLTEAD IRLYPSIIRF DVVYVQHFKC NLKTIRDGFP 301 YLHLWLINLY WNYAEFRFTT DFNHIKLFYI RMEVSRNKIN QFGIVPLGPK 351 PDISRL*

Amino Acid Sequence (or in FASTA format)

       1  MSVSYKGTIS KTHSVFKPEK GRYYIYGALG CPFTHRAILA RSLKKLEPVL
      51  GLVLSHWQLD SKGARFLPAP HRPEKYKERF FTATGGIASA KLDESEELGD
     101  VNNDSARLFV DGAFDPVENI SRLSELYYLN DPKYPGTKFT VPVLWDSKTR
     151  KIVNNESGDI IRILNSGVFD EFIQSEETNV IDLVPHDLID EIDKNIKWVH
     201  PKINLGVYKV GLAENGKIYE TEVKTLFENL QKMECVLKEN YKRLEEQFSG
     251  NKQKILAKYF VLGQRLTEAD IRLYPSIIRF DVVYVQHFKC NLKTIRDGFP
     301  YLHLWLINLY WNYAEFRFTT DFNHIKLFYI RMEVSRNKIN QFGIVPLGPK
     351  PDISRL*

external links for Gto1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Gto1p

1)	Herrero E (2005) Evolutionary relationships between Saccharomyces cerevisiae and other fungal species as determined from genome comparisons. Rev Iberoam Micol 22(4):217-22
2)	Garcera A, et al. (2006) Saccharomyces cerevisiae cells have three Omega class glutathione S-transferases acting as 1-Cys thiol transferases. Biochem J 398(2):187-96