VPS62/YGR141W Protein Information

Standard Name	Vps62p
Systematic Name	Ygr141wp
ORF Classification	Verified
Description	Vacuolar protein sorting (VPS) protein; required for cytoplasm to vacuole targeting of proteins; VPS62 has a paralog, TDA6, that arose from the whole genome duplication (1, 2)
Name Description	Vacuolar Protein Sorting 1

Experimental Data
Molecules/cell	623 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	467
Molecular Weight (Da)	54,515
Isoelectric Point (pI)	8.15

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Vps62p (InterPro)
Transmembrane Domains	There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 2 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013AF82 \| P53285 MIPS: YGR141W NCBI: 1323236 \| 1723717 \| 6321580 \| NP_011657.1 \| NM_001181270.1 GenBank/EMBL/DDBJ: DAA08232.1 \| Z72926

Amino Acid Sequence (or in FASTA format)
1 MRISKNSHKR QRTRLYFLVT FIIYSIIPCR AVLVPWLDDD PFEATLLEMG 51 DEPWSKDILS STPPLHPSEV TEDNKSLKQR GNVPQYVIDN SPLLHLYSEE 101 KYWPADVKDF VKRFQLRDHS GEKIINEHLR DLSDLQEYYS VELENGTWGR 151 VSSEGTYMTS LDDFDKGPDW LLGEQPEYGT GHIKKAPAVL FVVDKGNGWV 201 DAFWFYFYPF NWGPYIMGSG PWGNHVGDWE HSLVRFYKGE PQYLWMSAHG 251 GGSAYKFEAI EKIKRLRRVD GKLTNEVIKK PLIFSARGTH AHYASVGQHA 301 HDVPFFFMPL SDFTDRGPLW DPSLNYYAYT VTVGEKMTPC GAEETKMGLE 351 WLSFKGAWGD KQLRPRDPRQ KWCPFQWKYI DGPKGPLFKN MERVSLCQRF 401 KWWNFWKGCP ARRYIKRGEG LDAEKNDLVG DNCGILLYNI RPKWLRSILR 451 FLTWRGSVCF IMDYFTG*

Amino Acid Sequence (or in FASTA format)

       1  MRISKNSHKR QRTRLYFLVT FIIYSIIPCR AVLVPWLDDD PFEATLLEMG
      51  DEPWSKDILS STPPLHPSEV TEDNKSLKQR GNVPQYVIDN SPLLHLYSEE
     101  KYWPADVKDF VKRFQLRDHS GEKIINEHLR DLSDLQEYYS VELENGTWGR
     151  VSSEGTYMTS LDDFDKGPDW LLGEQPEYGT GHIKKAPAVL FVVDKGNGWV
     201  DAFWFYFYPF NWGPYIMGSG PWGNHVGDWE HSLVRFYKGE PQYLWMSAHG
     251  GGSAYKFEAI EKIKRLRRVD GKLTNEVIKK PLIFSARGTH AHYASVGQHA
     301  HDVPFFFMPL SDFTDRGPLW DPSLNYYAYT VTVGEKMTPC GAEETKMGLE
     351  WLSFKGAWGD KQLRPRDPRQ KWCPFQWKYI DGPKGPLFKN MERVSLCQRF
     401  KWWNFWKGCP ARRYIKRGEG LDAEKNDLVG DNCGILLYNI RPKWLRSILR
     451  FLTWRGSVCF IMDYFTG*

external links for Vps62p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Vps62p

1)	Bonangelino CJ, et al. (2002) Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol Biol Cell 13(7):2486-501
2)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41