VAS1/YGR094W Protein Information

Standard Name	Vas1p
Systematic Name	Ygr094wp
ORF Classification	Verified
Description	Mitochondrial and cytoplasmic valyl-tRNA synthetase (1, 2)
Name Description	VAlyl-tRNA Synthetase

Experimental Data
Molecules/cell	358 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	1,104
Molecular Weight (Da)	125,769
Isoelectric Point (pI)	6.94

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Vas1p (InterPro)
Physical Interactions	There are 33 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000052FAE \| P07806 MIPS: YGR094W NCBI: 1323141 \| 1711655 \| 173164 \| 553149 \| 553150 \| 6321531 \| NP_011608.1 GenBank/EMBL/DDBJ: DAA08187.1 \| J02719 \| M18392 \| Z72879
External Classifications	EC: 6.1.1.9 [Valine--tRNA ligase]

Amino Acid Sequence (or in FASTA format)
1 MNKWLNTLSK TFTFRLLNCH YRRSLPLCQN FSLKKSLTHN QVRFFKMSDL 51 DNLPPVDPKT GEVIINPLKE DGSPKTPKEI EKEKKKAEKL LKFAAKQAKK 101 NAAATTGASQ KKPKKKKEVE PIPEFIDKTV PGEKKILVSL DDPALKAYNP 151 ANVESSWYDW WIKTGVFEPE FTADGKVKPE GVFCIPAPPP NVTGALHIGH 201 ALTIAIQDSL IRYNRMKGKT VLFLPGFDHA GIATQSVVEK QIWAKDRKTR 251 HDYGREAFVG KVWEWKEEYH SRIKNQIQKL GASYDWSREA FTLSPELTKS 301 VEEAFVRLHD EGVIYRASRL VNWSVKLNTA ISNLEVENKD VKSRTLLSVP 351 GYDEKVEFGV LTSFAYPVIG SDEKLIIATT RPETIFGDTA VAVHPDDDRY 401 KHLHGKFIQH PFLPRKIPII TDKEAVDMEF GTGAVKITPA HDQNDYNTGK 451 RHNLEFINIL TDDGLLNEEC GPEWQGMKRF DARKKVIEQL KEKNLYVGQE 501 DNEMTIPTCS RSGDIIEPLL KPQWWVSQSE MAKDAIKVVR DGQITITPKS 551 SEAEYFHWLG NIQDWCISRQ LWWGHRCPVY FINIEGEEHD RIDGDYWVAG 601 RSMEEAEKKA AAKYPNSKFT LEQDEDVLDT WFSSGLWPFS TLGWPEKTKD 651 METFYPFSML ETGWDILFFW VTRMILLGLK LTGSVPFKEV FCHSLVRDAQ 701 GRKMSKSLGN VIDPLDVITG IKLDDLHAKL LQGNLDPREV EKAKIGQKES 751 YPNGIPQCGT DAMRFALCAY TTGGRDINLD ILRVEGYRKF CNKIYQATKF 801 ALMRLGDDYQ PPATEGLSGN ESLVEKWILH KLTETSKIVN EALDKRDFLT 851 STSSIYEFWY LICDVYIENS KYLIQEGSAI EKKSAKDTLY ILLDNALKLI 901 HPFMPFISEE MWQRLPKRST EKAASIVKAS YPVYVSEYDD VKSANAYDLV 951 LNITKEARSL LSEYNILKNG KVFVESNHEE YFKTAEDQKD SIVSLIKAID 1001 EVTVVRDASE IPEGCVLQSV NPEVNVHLLV KGHVDIDAEI AKVQKKLEKA 1051 KKSKNGIEQT INSKDYETKA NTQAKEANKS KLDNTVAEIE GLEATIENLK 1101 RLKL*

Amino Acid Sequence (or in FASTA format)

       1  MNKWLNTLSK TFTFRLLNCH YRRSLPLCQN FSLKKSLTHN QVRFFKMSDL
      51  DNLPPVDPKT GEVIINPLKE DGSPKTPKEI EKEKKKAEKL LKFAAKQAKK
     101  NAAATTGASQ KKPKKKKEVE PIPEFIDKTV PGEKKILVSL DDPALKAYNP
     151  ANVESSWYDW WIKTGVFEPE FTADGKVKPE GVFCIPAPPP NVTGALHIGH
     201  ALTIAIQDSL IRYNRMKGKT VLFLPGFDHA GIATQSVVEK QIWAKDRKTR
     251  HDYGREAFVG KVWEWKEEYH SRIKNQIQKL GASYDWSREA FTLSPELTKS
     301  VEEAFVRLHD EGVIYRASRL VNWSVKLNTA ISNLEVENKD VKSRTLLSVP
     351  GYDEKVEFGV LTSFAYPVIG SDEKLIIATT RPETIFGDTA VAVHPDDDRY
     401  KHLHGKFIQH PFLPRKIPII TDKEAVDMEF GTGAVKITPA HDQNDYNTGK
     451  RHNLEFINIL TDDGLLNEEC GPEWQGMKRF DARKKVIEQL KEKNLYVGQE
     501  DNEMTIPTCS RSGDIIEPLL KPQWWVSQSE MAKDAIKVVR DGQITITPKS
     551  SEAEYFHWLG NIQDWCISRQ LWWGHRCPVY FINIEGEEHD RIDGDYWVAG
     601  RSMEEAEKKA AAKYPNSKFT LEQDEDVLDT WFSSGLWPFS TLGWPEKTKD
     651  METFYPFSML ETGWDILFFW VTRMILLGLK LTGSVPFKEV FCHSLVRDAQ
     701  GRKMSKSLGN VIDPLDVITG IKLDDLHAKL LQGNLDPREV EKAKIGQKES
     751  YPNGIPQCGT DAMRFALCAY TTGGRDINLD ILRVEGYRKF CNKIYQATKF
     801  ALMRLGDDYQ PPATEGLSGN ESLVEKWILH KLTETSKIVN EALDKRDFLT
     851  STSSIYEFWY LICDVYIENS KYLIQEGSAI EKKSAKDTLY ILLDNALKLI
     901  HPFMPFISEE MWQRLPKRST EKAASIVKAS YPVYVSEYDD VKSANAYDLV
     951  LNITKEARSL LSEYNILKNG KVFVESNHEE YFKTAEDQKD SIVSLIKAID
    1001  EVTVVRDASE IPEGCVLQSV NPEVNVHLLV KGHVDIDAEI AKVQKKLEKA
    1051  KKSKNGIEQT INSKDYETKA NTQAKEANKS KLDNTVAEIE GLEATIENLK
    1101  RLKL*

external links for Vas1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Vas1p

1)	Chatton B, et al. (1988) The yeast VAS1 gene encodes both mitochondrial and cytoplasmic valyl-tRNA synthetases. J Biol Chem 263(1):52-7
2)	Jordana X, et al. (1987) Structure of the yeast valyl-tRNA synthetase gene (VASI) and the homology of its translated amino acid sequence with Escherichia coli isoleucyl-tRNA synthetase. J Biol Chem 262(15):7189-94
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41