SPR3/YGR059W Protein Information

Standard Name	Spr3p
Systematic Name	Ygr059wp
ORF Classification	Verified
Description	Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; septin protein involved in sporulation; regulated by ABFI (1)
Name Description	SPorulation Regulated 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	512
Molecular Weight (Da)	59,845
Isoelectric Point (pI)	7.34

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Spr3p (InterPro)
Physical Interactions	There are 55 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000135E6E \| P41901 MIPS: YGR059W NCBI: 1174429 \| 1323075 \| 398365431 \| 469462 \| 780796 \| NP_011573.3 \| NM_001181188.3 GenBank/EMBL/DDBJ: DAA08155.1 \| L31767 \| U24129 \| Z72844

Amino Acid Sequence (or in FASTA format)
1 MKSKGSRLST DCPVEFPKIV SGFAEEVKIR RQSSQGQYAV DSHPPKSPEL 51 KHRRQRSSSF VNGKCRNRDL PLLDNKKAQE INTNSHGQDI GIKNLPRQRE 101 LLNAKNGIDF TLMVAGQSGL GKTTFINSLF STSLIDDDIK ENKPIIRYKS 151 IVEGDGTHLN FNVIDTPGFG NNMDNAFTWR TMVNYIDEEI RSYIFQEEQP 201 DRTKMVDNRV HCCLYFLRPS NKGIDTLDVV TMKKLAKRVN LIPVIAKSDL 251 LTKEELKNFK TQVREIIRVQ DIPVCFFFGD EVLNATQDIF QKYPFSIIAS 301 NEYIFNEKGE KVKGRQYKWG AVDIENEKYC DFKILQKTIF DWNLIDLVES 351 TEDYYEKCRS EMLRTRLLKA RDCLTTKSVD ITEEQRKFLE EEMNFDEIEE 401 NKLKNYKCYE IINKTVMDKV ATEWDPEFIT RQLEAKKKFN ELSNREISKF 451 RDWKKSLFME QENFNQEIEQ LNHKLENLQL ECQDLEYKLL IGKSSNSHST 501 DSATLVNVHI KR*

Amino Acid Sequence (or in FASTA format)

       1  MKSKGSRLST DCPVEFPKIV SGFAEEVKIR RQSSQGQYAV DSHPPKSPEL
      51  KHRRQRSSSF VNGKCRNRDL PLLDNKKAQE INTNSHGQDI GIKNLPRQRE
     101  LLNAKNGIDF TLMVAGQSGL GKTTFINSLF STSLIDDDIK ENKPIIRYKS
     151  IVEGDGTHLN FNVIDTPGFG NNMDNAFTWR TMVNYIDEEI RSYIFQEEQP
     201  DRTKMVDNRV HCCLYFLRPS NKGIDTLDVV TMKKLAKRVN LIPVIAKSDL
     251  LTKEELKNFK TQVREIIRVQ DIPVCFFFGD EVLNATQDIF QKYPFSIIAS
     301  NEYIFNEKGE KVKGRQYKWG AVDIENEKYC DFKILQKTIF DWNLIDLVES
     351  TEDYYEKCRS EMLRTRLLKA RDCLTTKSVD ITEEQRKFLE EEMNFDEIEE
     401  NKLKNYKCYE IINKTVMDKV ATEWDPEFIT RQLEAKKKFN ELSNREISKF
     451  RDWKKSLFME QENFNQEIEQ LNHKLENLQL ECQDLEYKLL IGKSSNSHST
     501  DSATLVNVHI KR*

external links for Spr3p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Spr3p

1)	Ozsarac N, et al. (1995) The SPR3 gene encodes a sporulation-specific homologue of the yeast CDC3/10/11/12 family of bud neck microfilaments and is regulated by ABFI. Gene 164(1):157-62
2)	Holaway BL, et al. (1987) Transcriptional regulation of sporulation genes in yeast. Mol Gen Genet 210(3):449-59