RSC1/YGR056W Protein Information Help

Standard Name Rsc1p
Systematic Name Ygr056wp
ORF Classification Verified
Description Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; contains two essential bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook; RSC1 has a paralog, RSC2, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Remodel the Structure of Chromatin 5
Experimental Data
Molecules/cell 259 6
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 928
Molecular Weight (Da) 106,668
Isoelectric Point (pI) 6.49

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rsc1p (InterPro)
Physical Interactions There are 99 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001351E6 | P53236
MIPS: YGR056W
NCBI: 1323069 | 1723670 | 6321493 | 71064042 | NP_011570.1
GenBank/EMBL/DDBJ: DAA08152.1 | DQ115391 | Z72841
Amino Acid Sequence (or in FASTA format)
 
       1  MVEQDNGFLQ KLLKTQYDAV FHLKDENGIE IYPIFNVLPP KKEYPDYYII
      51  IRNPISLNTL KKRLPHYTSP QDFVNDFAQI PWNAMTYNAK DSVIYKYAIL
     101  LESFIKGKIV HNIRKHYPEV TYPSLGRIPE IFAESMQPSD LSSNPINTQE
     151  NDEKAGLNPE MKMAFAKLDS SITERKPTNQ DYRMQQKNSP AFPTHSASIT
     201  PQPLASPTPV VNYANITSAH PKTHVRRGRP PVIDLPYVLR IKNILKMMRR
     251  EVDQNNKTLT LCFEKLPDRN EEPTYYSVIT DPICLMDIRK KVKSRKYRNF
     301  HTFEEDFQLM LTNFKLYYSQ DQSNIIRAQL LEKNFNRLVR IELSKPDEDY
     351  LPEGELRYPL DDVEINDEKY QIGDWVLLHN PNDINKPIVG QIFRLWSTTD
     401  GNKWLNACWY FRPEQTVHRV DRLFYKNEVM KTGQYRDHPI QDIKGKCYVI
     451  HFTRFQRGDP STKVNGPQFV CEFRYNESDK VFNKIRTWKA CLPEELRDQD
     501  EPTIPVNGRK FFKYPSPIAD LLPANATLND KVPEPTEGAP TAPPLVGAVY
     551  LGPKLERDDL GEYSTSDDCP RYIIRPNDPP EEGKIDYETG TIITDTLTTS
     601  SMPRVNSSST IRLPTLKQTK SIPSSNFRSS SNTPLLHQNF NQTSNFLKLE
     651  NMNNSSHNLL SHPSVPKFQS PSLLEQSSRS KYHSAKKQTQ LSSTAPKKPA
     701  SKSFTLSSMI NTLTAHTSKY NFNHIVIEAP GAFVVPVPME KNIRTIQSTE
     751  RFSRSNLKNA QNLGNTAIND INTANEQIIW FKGPGVKITE RVIDSGNDLV
     801  RVPLNRWFCK NKRRKLDYED IEEDVMEPPN DFSEDMIANI FNPPPSLNLD
     851  MDLNLSPSSN NSSNFMDLST IASGDNDGKE CDTAEESEDE NEDTEDEHEI
     901  EDIPTTSAFG LNSSAEYLAF RLREFNKL*

external links for Rsc1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rsc1p
1) Lorch Y, et al.  (1998) Activated RSC-nucleosome complex and persistently altered form of the nucleosome. Cell 94(1):29-34
2) Neely KE and Workman JL  (2002) The complexity of chromatin remodeling and its links to cancer. Biochim Biophys Acta 1603(1):19-29
3) Bungard D, et al.  (2004) RSC1 and RSC2 are required for expression of mid-late sporulation-specific genes in Saccharomyces cerevisiae. Eukaryot Cell 3(4):910-8
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Cairns BR, et al.  (1996) RSC, an essential, abundant chromatin-remodeling complex. Cell 87(7):1249-60
6) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41