YGR054W Protein Information Help

Systematic Name Ygr054wp
ORF Classification Verified
Description Eukaryotic initiation factor (eIF) 2A; associates specifically with both 40S subunits and 80 S ribosomes, and interacts genetically with both eIF5b and eIF4E; homologous to mammalian eIF2A (1, 2)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 642
Molecular Weight (Da) 71,304
Isoelectric Point (pI) 9.53

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ygr054wp (InterPro)
Physical Interactions There are 62 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052FD5 | P53235
MIPS: YGR054W
NCBI: 1323065 | 1723669 | 1945319 | 398365397 | 71064040 | NP_011568.3
GenBank/EMBL/DDBJ: DAA08150.1 | DQ115391 | Z72839 | Z72840
Amino Acid Sequence (or in FASTA format)
 
       1  MSSQFFLKTS QDIELFQSYP TFEQSNTNSK DFPVISSVLS PCGRFLALST
      51  KENVKVFTGP CLDNVLLTMK LSDVYDLHFS PAGNYLSTWE RASIQDPNHK
     101  NVKVWYLNKP FKKDCVSEDI VPAYEYQAKS QSGWFLQFSK LDNYGLRLFK
     151  HDLKIVKLSS ANADNFDFQS PFAVLSDDET SQHFTTYLIS PAEHPTICTF
     201  TPEKGGKPAQ LIIWALSEGK ITKKIASKTF FKADSCQLKW NPLGNAILCL
     251  AITDFDSSNK SYYGENTLYL LSFQGVNGTL GGNSVRVSLT TGPVHDFTWS
     301  PTSRQFGVIA GYMPATISFF DLRGNVVHSL PQQAKNTMLF SPSGHYILIA
     351  GFGNLQGSVE ILDRLDKFKC VSKFDATNTS VCKWSPGGEF IMTATTSPRL
     401  RVDNGVKIWH VSGSLVFVKE FKELLKVDWR SPCNYKTLEN KDEAFFENHI
     451  INNWEPLPDS TTSSLDPKIS NKSELQIHSS VQEYISQHPS REASSNGNGS
     501  KAKAGGAYKP PHARRTGGGR IVPGVPPGAA KKTIPGLVPG MSANKDANTK
     551  NRRRRANKKS SETSPDSTPA PSAPASTNAP TNNKETSPEE KKIRSLLKKL
     601  RAIETLKERQ AVGDKLEDTQ VLKIQTEEKV LKDLEKLGWK DE*

external links for Ygr054wp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Ygr054wp
1) Zoll WL, et al.  (2002) Characterization of mammalian eIF2A and identification of the yeast homolog. J Biol Chem 277(40):37079-87
2) Komar AA, et al.  (2005) Novel characteristics of the biological properties of the yeast Saccharomyces cerevisiae eukaryotic initiation factor 2A. J Biol Chem 280(16):15601-11