NQM1/YGR043C Protein Information

Standard Name	Nqm1p 1
Systematic Name	Ygr043cp
ORF Classification	Verified
Description	Transaldolase of unknown function; transcription is repressed by Mot1p and induced by alpha-factor and during diauxic shift; NQM1 has a paralog, TAL1, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description	Non-Quiescent Mutant

Experimental Data
Molecules/cell	1920 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	333
Molecular Weight (Da)	37,253
Isoelectric Point (pI)	6.35

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Nqm1p (InterPro)
Physical Interactions	There are 8 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013688E \| P53228 MIPS: YGR043C NCBI: 1323043 \| 1729826 \| 226438171 \| 226438172 \| 45269555 \| 6321480 \| NP_011557.1 GenBank/EMBL/DDBJ: DAA08142.1 \| AY557832 \| Z72828
External Classifications	EC: 2.2.1.2 [Transaldolase]

Amino Acid Sequence (or in FASTA format)
1 MSEPSEKKQK VATSSLEQLK KAGTHVVADS GDFEAISKYE PQDSTTNPSL 51 ILAASKLEKY ARFIDAAVEY GRKHGKTDHE KIENAMDKIL VEFGTQILKV 101 VPGRVSTEVD ARLSFDKKAT VKKALHIIKL YKDAGVPKER VLIKIASTWE 151 GIQAARELEV KHGIHCNMTL LFSFTQAVAC AEANVTLISP FVGRIMDFYK 201 ALSGKDYTAE TDPGVLSVKK IYSYYKRHGY ATEVMAASFR NLDELKALAG 251 IDNMTLPLNL LEQLYESTDP IENKLNSESA KEEGVEKVSF INDEPHFRYV 301 LNEDQMATEK LSDGIRKFSA DIEALYKLVE EKM*

Amino Acid Sequence (or in FASTA format)

       1  MSEPSEKKQK VATSSLEQLK KAGTHVVADS GDFEAISKYE PQDSTTNPSL
      51  ILAASKLEKY ARFIDAAVEY GRKHGKTDHE KIENAMDKIL VEFGTQILKV
     101  VPGRVSTEVD ARLSFDKKAT VKKALHIIKL YKDAGVPKER VLIKIASTWE
     151  GIQAARELEV KHGIHCNMTL LFSFTQAVAC AEANVTLISP FVGRIMDFYK
     201  ALSGKDYTAE TDPGVLSVKK IYSYYKRHGY ATEVMAASFR NLDELKALAG
     251  IDNMTLPLNL LEQLYESTDP IENKLNSESA KEEGVEKVSF INDEPHFRYV
     301  LNEDQMATEK LSDGIRKFSA DIEALYKLVE EKM*

external links for Nqm1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Nqm1p

1)	Huang H, et al. (2008) The crystal structure and identification of NQM1/YGR043C, a transaldolase from Saccharomyces cerevisiae. Proteins 73(4):1076-1081
2)	Dasgupta A, et al. (2002) Mot1 activates and represses transcription by direct, ATPase-dependent mechanisms. Proc Natl Acad Sci U S A 99(5):2666-71
3)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41