ECT1/YGR007W Protein Information

Standard Name	Ect1p 1
Systematic Name	Ygr007wp
Alias	Muq1p 2
ORF Classification	Verified
Description	Ethanolamine-phosphate cytidylyltransferase, catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases (1, 3, 4)
Name Description	Ethanolamine-phosphate CytidylylTransferase 1

Experimental Data
Molecules/cell	4700 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	323
Molecular Weight (Da)	36,863
Isoelectric Point (pI)	6.44

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ect1p (InterPro)
Physical Interactions	There are 2 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000129BA4 \| P33412 MIPS: YGR007W NCBI: 1322965 \| 311122 \| 45269551 \| 462660 \| 6321444 \| 854670 \| NP_011521.1 GenBank/EMBL/DDBJ: DAA08105.1 \| AY557830 \| D50644 \| L03536 \| Z72792
External Classifications	EC: 2.7.7.14 [Ethanolamine-phosphate cytidylyltransferase]

Amino Acid Sequence (or in FASTA format)
1 MTVNLDPDKV WIDGCFDFTH HGHAGAILQA RRTVSKENGK LFCGVHTDED 51 IQHNKGTPVM NSSERYEHTR SNRWCSEVVE AAPYVTDPNW MDKYQCQYVV 101 HGDDITIDAN GEDCYKLVKE MGRFKVVKRT YGVSTTEIIH RILTKKSLPP 151 THPDYYPTTQ ELSFYSVAQD AVSKHCYVFQ RDLDNVLVNG GYKFDAEDCV 201 YVDGDFDLFH MGDIDQLRKL KMDLHPDKKL IVGITTSDYS STIMTMKERV 251 LSVLSCKYVD AVIIDADATS MSQYNCEKYH IGTAVLTAAG KFSEYLTKEL 301 IVKRVESQRE VYIARNQKKG MSI*

Amino Acid Sequence (or in FASTA format)

       1  MTVNLDPDKV WIDGCFDFTH HGHAGAILQA RRTVSKENGK LFCGVHTDED
      51  IQHNKGTPVM NSSERYEHTR SNRWCSEVVE AAPYVTDPNW MDKYQCQYVV
     101  HGDDITIDAN GEDCYKLVKE MGRFKVVKRT YGVSTTEIIH RILTKKSLPP
     151  THPDYYPTTQ ELSFYSVAQD AVSKHCYVFQ RDLDNVLVNG GYKFDAEDCV
     201  YVDGDFDLFH MGDIDQLRKL KMDLHPDKKL IVGITTSDYS STIMTMKERV
     251  LSVLSCKYVD AVIIDADATS MSQYNCEKYH IGTAVLTAAG KFSEYLTKEL
     301  IVKRVESQRE VYIARNQKKG MSI*

external links for Ect1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ect1p

1)	Min-Seok R, et al. (1996) Isolation and characterization of ECT1 gene encoding CTP: phosphoethanolamine cytidylyltransferase of Saccharomyces cerevisiae. J Biochem 120(5):1040-7
2)	Horowitz DS and Abelson J (1993) A U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae. Mol Cell Biol 13(5):2959-70
3)	Nakashima A, et al. (1997) Cloning of a human cDNA for CTP-phosphoethanolamine cytidylyltransferase by complementation in vivo of a yeast mutant. J Biol Chem 272(14):9567-72
4)	Miura S, et al. (2000) Screening of genes involved in isooctane tolerance in saccharomyces cerevisiae by using mRNA differential display Appl Environ Microbiol 66(11):4883-9
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41