PEX31/YGR004W Protein Information Help

Standard Name Pex31p 1
Systematic Name Ygr004wp
ORF Classification Verified
Description Peroxisomal integral membrane protein; involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p; PEX31 has a paralog, PEX30, that arose from the whole genome duplication (1, 2)
Name Description PEroXisome related 1
Experimental Data
Molecules/cell 238 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 462
Molecular Weight (Da) 52,942
Isoelectric Point (pI) 10.15

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Pex31p (InterPro)
Transmembrane Domains There are 4 total predicted transmembrane domains (TMHMM)
Physical Interactions There are 8 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013AF1E | P53203
MIPS: YGR004W
NCBI: 1322959 | 1723642 | 6321441 | NP_011518.1 | NM_001181133.1
GenBank/EMBL/DDBJ: CAA96987.1 | DAA08102.1 | Z72789
Amino Acid Sequence (or in FASTA format)
       1  MSEINNENLE PTSSTVAEST ESKNKHIRSA LRKRRGKLSA QTYEEDQEAI
      51  LSSPLLTSTP KTVSRSLVRL YPYLIVVDNF LSIITWSNDN VSANLLGIFL
     101  FTVCVLYFGF ITRYFGHLMI VGIIWVYLLI DKHVQETMAS CPSLDDIIHV
     151  MDRVSMKSSA VLSPITILSA QDVRRLLFTI AFLSPVYIFL TVFVLSPNYL
     201  MLIGGLYVLT YHSKLIRRMR RYLWKFRVVR LLVFFITGLD LGGPDNNRRL
     251  FASVNKKIRS FVWNEVGNTS NTKKTVLFKV ALFENQRRWL GIGWTSTMLS
     301  YERASWTDEF LNTSPSPEVF TLPEEQSGMA WEWHDKDWML DLTNDGIIQL
     351  PASAAKTKVK PGADEGFIYY DNTWNNPSAT DTYKKYTRRR RWIRTATVTT
     401  TYDDEPTVEK ATPNSHALKS EENNRVRKRK VSFSTANEVH IIPSSDSSKL
     451  IQISDVSMSP SL*                                        

external links for Pex31p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
YGOB CYC2008 (complexes) MIPS YPL+
YOGY Complexome Pfam domains YeastGFP

DIP
YeastRC Public Image Repository

GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Pex31p
1) Vizeacoumar FJ, et al.  (2004) Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae. Mol Biol Cell 15(2):665-77
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41