MNT2/YGL257C Protein Information

Standard Name	Mnt2p 1
Systematic Name	Ygl257cp
ORF Classification	Verified
Description	Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans (1)
Name Description	MaNnosylTransferase 1

Experimental Data
Molecules/cell	1170 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	558
Molecular Weight (Da)	64,852
Isoelectric Point (pI)	5.46

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mnt2p (InterPro)
Transmembrane Domains	There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 1 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012F2A9 \| P53059 MIPS: YGL257C NCBI: 1150582 \| 1322939 \| 1723985 \| 6321180 \| NP_011257.1 GenBank/EMBL/DDBJ: DAA07862.1 \| X94357 \| Z72779
External Classifications	EC: 2.4.1- [Hexosyltransferases] EC: 2.4.1.- [Hexosyltransferases]

Amino Acid Sequence (or in FASTA format)
1 MRRKNRLFIL VVLLGIVLVV YYSQLNSLDL VEPVQSSSSG NGGCWSYYEG 51 LTPGWLNDFY DVNQITPNPA KDVIELVTRI KIFFNCLQQV DGHNIQRLRD 101 IEKKLFPYIN FEKLETDESA FWHTTTRWNG EVYHASMLEF DPKNHQFLRS 151 KPINFDTGLS FWENWLHTVT QSGSKGIVIS ASDVQLNETI RLLKVLRFIK 201 NDYPIQIVHN ADLSQDSMKS IIKYARSLDT AEYPAQELWF LNVHSLLNPK 251 YSKKFTTYSN KWLALTFSSF EIPILMDSDT VPFVSIEKFY ELEEFQKTGV 301 LFFKDRVISD DLFESSELKI LREIVYGCIG LDLEDESKIH EQVEDPVVAQ 351 VLENMFIKKY KHHLESGLVI LHKGKHLFSM LTSIALQFSP IAEYFHGDKD 401 FFWLGELLSN NRFTFHPVDA SNIGQLGNVV SKESTGEFYQ ICSVQLSHTD 451 RDGSLLWLNG GLNICKKTSW EYDYEHRQRL NDMFQNADEL REYYASPVKL 501 EGIIIPDTSI SGWINSGECF LFNYCTLFKE GEFGKLIKFK EDEKLRLSQI 551 VDIWNKDI*

Amino Acid Sequence (or in FASTA format)

       1  MRRKNRLFIL VVLLGIVLVV YYSQLNSLDL VEPVQSSSSG NGGCWSYYEG
      51  LTPGWLNDFY DVNQITPNPA KDVIELVTRI KIFFNCLQQV DGHNIQRLRD
     101  IEKKLFPYIN FEKLETDESA FWHTTTRWNG EVYHASMLEF DPKNHQFLRS
     151  KPINFDTGLS FWENWLHTVT QSGSKGIVIS ASDVQLNETI RLLKVLRFIK
     201  NDYPIQIVHN ADLSQDSMKS IIKYARSLDT AEYPAQELWF LNVHSLLNPK
     251  YSKKFTTYSN KWLALTFSSF EIPILMDSDT VPFVSIEKFY ELEEFQKTGV
     301  LFFKDRVISD DLFESSELKI LREIVYGCIG LDLEDESKIH EQVEDPVVAQ
     351  VLENMFIKKY KHHLESGLVI LHKGKHLFSM LTSIALQFSP IAEYFHGDKD
     401  FFWLGELLSN NRFTFHPVDA SNIGQLGNVV SKESTGEFYQ ICSVQLSHTD
     451  RDGSLLWLNG GLNICKKTSW EYDYEHRQRL NDMFQNADEL REYYASPVKL
     501  EGIIIPDTSI SGWINSGECF LFNYCTLFKE GEFGKLIKFK EDEKLRLSQI
     551  VDIWNKDI*

external links for Mnt2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Mnt2p

1)	Romero PA, et al. (1999) Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides. Glycobiology 9(10):1045-51
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41