YPT32/YGL210W Protein Information

Standard Name	Ypt32p 1
Systematic Name	Ygl210wp
ORF Classification	Verified
Description	Rab family GTPase involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; protein abundance increases in response to DNA replication stress; YPT32 has a paralog, YPT31, that arose from the whole genome duplication (1, 2, 3, 4, 5, 6)
Name Description	Yeast Protein Two 1

Experimental Data
Molecules/cell	4300 7

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	222
Molecular Weight (Da)	24,520
Isoelectric Point (pI)	5.22

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ypt32p (InterPro)
Physical Interactions	There are 42 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013BD27 \| P51996 MIPS: YGL210W NCBI: 1322850 \| 1655723 \| 1730881 \| 354459567 \| 354459568 \| 354459569 \| 45270902 \| 6321228 \| 927543 \| NP_011305.1 GenBank/EMBL/DDBJ: DAA07906.1 \| AY558506 \| U33754 \| X72834 \| Z72732

Amino Acid Sequence (or in FASTA format)
1 MSNEDYGYDY DYLFKIVLIG DSGVGKSNLL SRFTTDEFNI ESKSTIGVEF 51 ATRTIEVENK KIKAQIWDTA GQERYRAITS AYYRGAVGAL IVYDISKSSS 101 YENCNHWLTE LRENADDNVA VGLIGNKSDL AHLRAVPTDE AKNFAMENQM 151 LFTETSALNS DNVDKAFREL IVAIFQMVSK HQVDLSGSGT NNMGSNGAPK 201 GPTISLTPAP KEDKKKKSSN CC*

Amino Acid Sequence (or in FASTA format)

       1  MSNEDYGYDY DYLFKIVLIG DSGVGKSNLL SRFTTDEFNI ESKSTIGVEF
      51  ATRTIEVENK KIKAQIWDTA GQERYRAITS AYYRGAVGAL IVYDISKSSS
     101  YENCNHWLTE LRENADDNVA VGLIGNKSDL AHLRAVPTDE AKNFAMENQM
     151  LFTETSALNS DNVDKAFREL IVAIFQMVSK HQVDLSGSGT NNMGSNGAPK
     201  GPTISLTPAP KEDKKKKSSN CC*

external links for Ypt32p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ypt32p

1)	Benli M, et al. (1996) Two GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeast. EMBO J 15(23):6460-75
2)	Jedd G, et al. (1997) Two new Ypt GTPases are required for exit from the yeast trans-Golgi compartment. J Cell Biol 137(3):563-80
3)	Lazar T, et al. (1997) Vesicular transport: how many Ypt/Rab-GTPases make a eukaryotic cell? Trends Biochem Sci 22(12):468-72
4)	Wang W and Ferro-Novick S (2002) A Ypt32p exchange factor is a putative effector of Ypt1p. Mol Biol Cell 13(9):3336-43
5)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
6)	Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
7)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41