RPL1B/YGL135W Protein Information Help

Standard Name Rpl1bp
Systematic Name Ygl135wp
Alias Ssm2p
ORF Classification Verified
Description Ribosomal 60S subunit protein L1B; N-terminally acetylated; homologous to mammalian ribosomal protein L10A and bacterial L1; RPL1B has a paralog, RPL1A, that arose from the whole genome duplication; rpl1a rpl1b double null mutation is lethal (1, 2, 3, 4, 5)
Name Description Ribosomal Protein of the Large subunit
Gene Product L1 5 , L1B 2
Experimental Data
Molecules/cell 265000 6
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 217
Molecular Weight (Da) 24,486
Isoelectric Point (pI) 10.51

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rpl1bp (InterPro)
Physical Interactions There are 110 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000132EB6 | P0CX44
MIPS: YGL135W
NCBI: 1246843 | 1322706 | 338819280 | 398364437 | 6325036 | 732951 | NP_011380.3 | NP_015104.1 | NM_001181000.3 | NM_001184034.1
GenBank/EMBL/DDBJ: CAA50315.1 | CAA63361.1 | CAA96846.1 | DAA07975.1 | X70986 | X92670 | Z72657
Amino Acid Sequence (or in FASTA format)
       1  MSKITSSQVR EHVKELLKYS NETKKRNFLE TVELQVGLKN YDPQRDKRFS
      51  GSLKLPNCPR PNMSICIFGD AFDVDRAKSC GVDAMSVDDL KKLNKNKKLI
     101  KKLSKKYNAF IASEVLIKQV PRLLGPQLSK AGKFPTPVSH NDDLYGKVTD
     151  VRSTIKFQLK KVLCLAVAVG NVEMEEDVLV NQILMSVNFF VSLLKKNWQN
     201  VGSLVVKSSM GPAFRLY*                                   

external links for Rpl1bp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
Aspergillus (AspGD) CYC2008 (complexes) MIPS YPL+
YGOB Complexome Pfam domains YeastGFP
YOGY GeneMANIA YeastRC Structure Prediction (Seattle) YeastRC Public Image Repository

IMP


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rpl1bp
1) Petitjean A, et al.  (1995) The duplicated Saccharomyces cerevisiae gene SSM1 encodes a eucaryotic homolog of the eubacterial and archaebacterial L1 ribosomal proteins. Mol Cell Biol 15(9):5071-81
2) Planta RJ and Mager WH  (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7
3) Lecompte O, et al.  (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Jenner L, et al.  (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol 22(6):759-67
6) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41