TAF6/YGL112C Protein Information

Standard Name	Taf6p 1
Systematic Name	Ygl112cp
Alias	Taf60p
ORF Classification	Verified
Description	Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4 (1, 2, 3)
Name Description	TATA binding protein-Associated Factor
Gene Product	TafII60

Experimental Data
Molecules/cell	6510 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	516
Molecular Weight (Da)	57,901
Isoelectric Point (pI)	5.17

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Taf6p (InterPro)
Physical Interactions	There are 418 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000052DE9 \| P53040 MIPS: YGL112C NCBI: 1310712 \| 1322661 \| 1729811 \| 51830327 \| 6321326 \| 840662 \| NP_011403.1 GenBank/EMBL/DDBJ: DAA07996.1 \| AY723809 \| L40145 \| X97644 \| Z72634

Amino Acid Sequence (or in FASTA format)
1 MSTQQQSYTI WSPQDTVKDV AESLGLENIN DDVLKALAMD VEYRILEIIE 51 QAVKFKRHSK RDVLTTDDVS KALRVLNVEP LYGYYDGSEV NKAVSFSKVN 101 TSGGQSVYYL DEEEVDFDRL INEPLPQVPR LPTFTTHWLA VEGVQPAIIQ 151 NPNLNDIRVS QPPFIRGAIV TALNDNSLQT PVTSTTASAS VTDTGASQHL 201 SNVKPGQNTE VKPLVKHVLS KELQIYFNKV ISTLTAKSQA DEAAQHMKQA 251 ALTSLRTDSG LHQLVPYFIQ FIAEQITQNL SDLQLLTTIL EMIYSLLSNT 301 SIFLDPYIHS LMPSILTLLL AKKLGGSPKD DSPQEIHEFL ERTNALRDFA 351 ASLLDYVLKK FPQAYKSLKP RVTRTLLKTF LDINRVFGTY YGCLKGVSVL 401 EGESIRFFLG NLNNWARLVF NESGITLDNI EEHLNDDSNP TRTKFTKEET 451 QILVDTVISA LLVLKKDLPD LYEGKGEKVT DEDKEKLLER CGVTIGFHIL 501 KRDDAKELIS AIFFGE*

Amino Acid Sequence (or in FASTA format)

       1  MSTQQQSYTI WSPQDTVKDV AESLGLENIN DDVLKALAMD VEYRILEIIE
      51  QAVKFKRHSK RDVLTTDDVS KALRVLNVEP LYGYYDGSEV NKAVSFSKVN
     101  TSGGQSVYYL DEEEVDFDRL INEPLPQVPR LPTFTTHWLA VEGVQPAIIQ
     151  NPNLNDIRVS QPPFIRGAIV TALNDNSLQT PVTSTTASAS VTDTGASQHL
     201  SNVKPGQNTE VKPLVKHVLS KELQIYFNKV ISTLTAKSQA DEAAQHMKQA
     251  ALTSLRTDSG LHQLVPYFIQ FIAEQITQNL SDLQLLTTIL EMIYSLLSNT
     301  SIFLDPYIHS LMPSILTLLL AKKLGGSPKD DSPQEIHEFL ERTNALRDFA
     351  ASLLDYVLKK FPQAYKSLKP RVTRTLLKTF LDINRVFGTY YGCLKGVSVL
     401  EGESIRFFLG NLNNWARLVF NESGITLDNI EEHLNDDSNP TRTKFTKEET
     451  QILVDTVISA LLVLKKDLPD LYEGKGEKVT DEDKEKLLER CGVTIGFHIL
     501  KRDDAKELIS AIFFGE*

external links for Taf6p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Taf6p

1)	Tora L (2002) A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription. Genes Dev 16(6):673-5
2)	Grant PA, et al. (1998) A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation. Cell 94(1):45-53
3)	Lee TI and Young RA (2000) Transcription of eukaryotic protein-coding genes. Annu Rev Genet 34:77-137
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41