TOS8/YGL096W Protein Information

Standard Name	Tos8p 1
Systematic Name	Ygl096wp
ORF Classification	Verified
Description	Homeodomain-containing protein and putative transcription factor; found associated with chromatin; target of SBF transcription factor; induced during meiosis and under cell-damaging conditions; TOS8 has a paralog, CUP9, that arose from the whole genome duplication (1, 2)
Name Description	Target Of Sbf 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	276
Molecular Weight (Da)	31,257
Isoelectric Point (pI)	11.05

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Tos8p (InterPro)
Physical Interactions	There are 7 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013B0D5 \| P53147 MIPS: YGL096W NCBI: 1322631 \| 1723892 \| 45270882 \| 6321342 \| NP_011419.1 GenBank/EMBL/DDBJ: DAA08010.1 \| AY558496 \| Z72618

Amino Acid Sequence (or in FASTA format)
1 MGTSIVNLNQ KIELPPIQVL FESLNRENET KPHFEERRLY QPNPSFVPRT 51 NIAVGSPVNP VPVSSPVFFI GPSPQRSIQN HNAIMTQNIR QYPVIYNNNR 101 EVISTGERNY IITVGGPPVT SSQPEYEHIS TPNFYQEQRL AQPHPVNESM 151 MIGGYTNPQP ISISRGKMLS GNISTNSVRG SNNGYSAKEK KHKAHGKRSN 201 LPKATVSILN KWLHEHVNNP YPTVQEKREL LAKTGLTKLQ ISNWFINARR 251 RKIFSGQNDA NNFRRKFSSS TNLAKF*

Amino Acid Sequence (or in FASTA format)

       1  MGTSIVNLNQ KIELPPIQVL FESLNRENET KPHFEERRLY QPNPSFVPRT
      51  NIAVGSPVNP VPVSSPVFFI GPSPQRSIQN HNAIMTQNIR QYPVIYNNNR
     101  EVISTGERNY IITVGGPPVT SSQPEYEHIS TPNFYQEQRL AQPHPVNESM
     151  MIGGYTNPQP ISISRGKMLS GNISTNSVRG SNNGYSAKEK KHKAHGKRSN
     201  LPKATVSILN KWLHEHVNNP YPTVQEKREL LAKTGLTKLQ ISNWFINARR
     251  RKIFSGQNDA NNFRRKFSSS TNLAKF*

external links for Tos8p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Tos8p

1)	Horak CE, et al. (2002) Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev 16(23):3017-33
2)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61