NBP35/YGL091C Protein Information

Standard Name	Nbp35p 1
Systematic Name	Ygl091cp
ORF Classification	Verified
Description	Essential iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Cfd1p that is involved in iron-sulfur protein assembly in the cytosol; similar to P-loop NTPases (1, 2, 3)
Name Description	Nucleotide Binding Protein 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	328
Molecular Weight (Da)	35,253
Isoelectric Point (pI)	4.32

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Nbp35p (InterPro)
Physical Interactions	There are 12 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000053288 \| P52920 MIPS: YGL091C NCBI: 1322621 \| 1360147 \| 1709228 \| 398364553 \| NP_011424.3 GenBank/EMBL/DDBJ: DAA08015.1 \| X95533 \| Z72613

Amino Acid Sequence (or in FASTA format)
1 MTEILPHVND EVLPAEYELN QPEPEHCPGP ESDMAGKSDA CGGCANKEIC 51 ESLPKGPDPD IPLITDNLSG IEHKILVLSG KGGVGKSTFA AMLSWALSAD 101 EDLQVGAMDL DICGPSLPHM LGCIKETVHE SNSGWTPVYV TDNLATMSIQ 151 YMLPEDDSAI IWRGSKKNLL IKKFLKDVDW DKLDYLVIDT PPGTSDEHIS 201 INKYMRESGI DGALVVTTPQ EVALLDVRKE IDFCKKAGIN ILGLVENMSG 251 FVCPNCKGES QIFKATTGGG EALCKELGIK FLGSVPLDPR IGKSCDMGES 301 FLDNYPDSPA SSAVLNVVEA LRDAVGDV*

Amino Acid Sequence (or in FASTA format)

       1  MTEILPHVND EVLPAEYELN QPEPEHCPGP ESDMAGKSDA CGGCANKEIC
      51  ESLPKGPDPD IPLITDNLSG IEHKILVLSG KGGVGKSTFA AMLSWALSAD
     101  EDLQVGAMDL DICGPSLPHM LGCIKETVHE SNSGWTPVYV TDNLATMSIQ
     151  YMLPEDDSAI IWRGSKKNLL IKKFLKDVDW DKLDYLVIDT PPGTSDEHIS
     201  INKYMRESGI DGALVVTTPQ EVALLDVRKE IDFCKKAGIN ILGLVENMSG
     251  FVCPNCKGES QIFKATTGGG EALCKELGIK FLGSVPLDPR IGKSCDMGES
     301  FLDNYPDSPA SSAVLNVVEA LRDAVGDV*

external links for Nbp35p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Nbp35p

1)	Vitale G, et al. (1996) NBP35 encodes an essential and evolutionary conserved protein in Saccharomyces cerevisiae with homology to a superfamily of bacterial ATPases. Gene 178(1-2):97-106
2)	Hausmann A, et al. (2005) The eukaryotic P loop NTPase Nbp35: an essential component of the cytosolic and nuclear iron-sulfur protein assembly machinery. Proc Natl Acad Sci U S A 102(9):3266-71
3)	Netz DJ, et al. (2007) The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol. Nat Chem Biol 3(5):278-86