TRP5/YGL026C Protein Information Help

Standard Name Trp5p 1, 2
Systematic Name Ygl026cp
ORF Classification Verified
Description Tryptophan synthase, catalyzes the last step of tryptophan biosynthesis; regulated by the general control system of amino acid biosynthesis (3, 4)
Name Description TRyPtophan requiring
Experimental Data
Molecules/cell 15500 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 707
Molecular Weight (Da) 76,626
Isoelectric Point (pI) 6.48

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Trp5p (InterPro)
Physical Interactions There are 22 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013764C | P00931
MIPS: YGL026C
NCBI: 1322496 | 136373 | 4674 | 4676 | 6321412 | NP_011489.1 | NM_001180891.1
GenBank/EMBL/DDBJ: DAA08073.1 | V01342 | V01343 | Z72548
External Classifications EC: 4.2.1.20 [Tryptophan synthase]
Amino Acid Sequence (or in FASTA format)
 
       1  MSEQLRQTFA NAKKENRNAL VTFMTAGYPT VKDTVPILKG FQDGGVDIIE
      51  LGMPFSDPIA DGPTIQLSNT VALQNGVTLP QTLEMVSQAR NEGVTVPIIL
     101  MGYYNPILNY GEERFIQDAA KAGANGFIIV DLPPEEALKV RNYINDNGLS
     151  LIPLVAPSTT DERLELLSHI ADSFVYVVSR MGTTGVQSSV ASDLDELISR
     201  VRKYTKDTPL AVGFGVSTRE HFQSVGSVAD GVVIGSKIVT LCGDAPEGKR
     251  YDVAKEYVQG ILNGAKHKVL SKDEFFAFQK ESLKSANVKK EILDEFDENH
     301  KHPIRFGDFG GQYVPEALHA CLRELEKGFD EAVADPTFWE DFKSLYSYIG
     351  RPSSLHKAER LTEHCQGAQI WLKREDLNHT GSHKINNALA QVLLAKRLGK
     401  KNVIAETGAG QHGVATATAC AKFGLTCTVF MGAEDVRRQA LNVFRMRILG
     451  AKVIAVTNGT KTLRDATSEA FRFWVTNLKT TYYVVGSAIG PHPYPTLVRT
     501  FQSVIGKETK EQFAAMNNGK LPDAVVACVG GGSNSTGMFS PFEHDTSVKL
     551  LGVEAGGDGV DTKFHSATLT AGRPGVFHGV KTYVLQDSDG QVHDTHSVSA
     601  GLDYPGVGPE LAYWKSTGRA QFIAATDAQA LLGFKLLSQL EGIIPALESS
     651  HAVYGACELA KTMKPDQHLV INISGRGDKD VQSVAEVLPK LGPKIGWDLR
     701  FEEDPSA*

external links for Trp5p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Trp5p
1) Balzi, E.  (1989) Personal Communication, Mortimer Map Edition 10
2) Plotkin, D.J.  (1978) Commitment to meiotic recombination: a temporal analysis. Ph.D Thesis
3) Zalkin H and Yanofsky C  (1982) Yeast gene TRP5: structure, function, regulation. J Biol Chem 257(3):1491-500
4) Moye WS and Zalkin H  (1985) Deletion mapping the yeast TRP5 control region. J Biol Chem 260(8):4718-23
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41