CWC21/YDR482C Protein Information Help

Standard Name Cwc21p 1
Systematic Name Ydr482cp
ORF Classification Verified
Description Protein involved in RNA splicing by the spliceosome; component of a complex containing Cef1p; interacts genetically with ISY1 and BUD13; may bind RNA; has similarity to S. pombe Cwf21p (1, 2)
Name Description Complexed With Cef1p 1
Experimental Data
Molecules/cell 556 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 135
Molecular Weight (Da) 15,762
Isoelectric Point (pI) 10.44

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Cwc21p (InterPro)
Physical Interactions There are 52 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00000698AA | Q03375
MIPS: YDR482C
NCBI: 398366637 | 45269491 | 73918943 | 927757 | NP_010770.3 | NM_001180790.3
GenBank/EMBL/DDBJ: AAB64929.1 | AAS56126.1 | DAA12315.1 | AY557800 | U33050
Amino Acid Sequence (or in FASTA format)
       1  MSYNGIGLKS AKGSSTSGHV QRSLASNNRR RPQGSQQQRQ QRQNAIKKAS
      51  HDKASRPLAV QKQIETHMEK REIEVQVSEL RDRLEEEETL SEEQIDKKCE
     101  ALRAKLTNEW QEQQRMSSLY TPRKARLTEE QHRHE*               

external links for Cwc21p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
Candida (CGD) CYC2008 (complexes) MIPS YPL+
YGOB Complexome Pfam domains YeastGFP
YOGY DIP YeastRC Structure Prediction (Seattle) YeastRC Public Image Repository

GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Cwc21p
1) Ohi MD, et al.  (2002) Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol 22(7):2011-24
2) Khanna M, et al.  (2009) A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300. RNA 15(12):2174-85
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41