DYN2/YDR424C Protein Information Help

Standard Name Dyn2p 1
Systematic Name Ydr424cp
Alias Slc1p 2
ORF Classification Verified
Description Cytoplasmic light chain dynein, microtubule motor protein; proposed to be involved in the assembly of the nuclear pore complex (2, 3, 4)
Name Description DYNein
Experimental Data
Molecules/cell 1310 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 92
Molecular Weight (Da) 10,441
Isoelectric Point (pI) 9.03

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Dyn2p (InterPro)
Physical Interactions There are 25 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000129A14 | Q02647
MIPS: YDR424C
NCBI: 1143275 | 2194167 | 2494224 | 380765155 | 380765157 | 6320632 | NP_010712.1
GenBank/EMBL/DDBJ: DAA12264.1 | U33007 | U36468
Amino Acid Sequence (or in FASTA format)
       1  MSDENKSTPI VKASDITDKL KEDILTISKD ALDKYQLERD IAGTVKKQLD
      51  VKYGNTWHVI VGKNFGSYVT HEKGHFVYFY IGPLAFLVFK TA*       

external links for Dyn2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Dyn2p
1) King SM, et al.  (1996) Brain cytoplasmic and flagellar outer arm dyneins share a highly conserved Mr 8,000 light chain. J Biol Chem 271(32):19358-66
2) Dick T, et al.  (1996) Molecular and genetic characterization of SLC1, a putative Saccharomyces cerevisiae homolog of the metazoan cytoplasmic dynein light chain 1. Mol Gen Genet 251(1):38-43
3) Holleran EA, et al.  (1998) The role of the dynactin complex in intracellular motility. Int Rev Cytol 182():69-109
4) Stelter P, et al.  (2007) Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex. Nat Cell Biol 9(7):788-96
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41