UTP4/YDR324C Protein Information Help

Standard Name Utp4p 1
Systematic Name Ydr324cp
ORF Classification Verified
Description Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; member of t-Utp subcomplex involved with transcription of 35S rRNA transcript (1, 2, 3, 4)
Name Description U Three Protein 1
Experimental Data
Molecules/cell 5440 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 776
Molecular Weight (Da) 87,801
Isoelectric Point (pI) 6.52

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Utp4p (InterPro)
Physical Interactions There are 197 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000053029 | Q06679
MIPS: YDR324C
NCBI: 398366489 | 59800441 | 915001 | NP_010611.3
GenBank/EMBL/DDBJ: DAA12167.1 | U32517
Amino Acid Sequence (or in FASTA format)
 
       1  MSSSLLSVLK EKSRSLKIRN KPVKMTSQER MIVHRCRFVD FTPATITSLA
      51  FSHKSNINKL TPSDLRLAIG RSNGNIEIWN PRNNWFQEMV IEGGKDRSIE
     101  GLCWSNVNGE SLRLFSIGGS TVVTEWDLAT GLPLRNYDCN SGVIWSISIN
     151  DSQDKLSVGC DNGTVVLIDI SGGPGVLEHD TILMRQEARV LTLAWKKDDF
     201  VIGGCSDGRI RIWSAQKNDE NMGRLLHTMK VDKAKKESTL VWSVIYLPRT
     251  DQIASGDSTG SIKFWDFQFA TLNQSFKAHD ADVLCLTTDT DNNYVFSAGV
     301  DRKIFQFSQN TNKSQKNNRW VNSSNRLLHG NDIRAICAYQ SKGADFLVSG
     351  GVEKTLVINS LTSFSNGNYR KMPTVEPYSK NVLVNKEQRL VVSWSESTVK
     401  IWTMGTDSST EQNYKLVCKL TLKDDQNIST CSLSPDGQVL VVGRPSTTKV
     451  FHLQPVGNKL KVTKLDNDLL LRTSTKLVKF IDNSKIVICS CEDDVFIVDL
     501  ESEEDEKPQE VELLEVTSTK SSIKVPYINR INHLEVDQNI AVISRGCGVV
     551  DILDLKARIS KPLARLNNFI TAVHINTSRK SVVVITADNK IYEFNMNLNS
     601  EAENEDSESV LTQWSKNNTD NLPKEWKTLK ENCVGIFSDI ENSSRLWFWG
     651  ATWISRIDFD VDFPINKRRK QKKRTHEGLT ITDESNFMND EEDDEDDDID
     701  MEISENLNVL LNQGNKIKST DVQRNEESSG HFFFTDKYKP LLFVDLISSN
     751  ELAIIERNPL TFHSKQKAFI QPKLVF*

external links for Utp4p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) BioPIXIE MIPS YeastGFP
Candida (CandidaDB) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Utp4p
1) Dragon F, et al.  (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417(6892):967-70
2) Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15
3) Gallagher JE, et al.  (2004) RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes Dev 18(20):2506-17
4) Perez-Fernandez J, et al.  (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41