PRP42/YDR235W Protein Information Help

Standard Name Prp42p
Systematic Name Ydr235wp
Alias Mud16p , Snu65p
ORF Classification Verified
Description U1 snRNP protein involved in splicing; required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats (1)
Name Description Pre-mRNA Processing
Experimental Data
Molecules/cell 1730 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 544
Molecular Weight (Da) 65,145
Isoelectric Point (pI) 8.08

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Prp42p (InterPro)
Physical Interactions There are 63 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00000530EF | Q03776
MIPS: YDR235W
NCBI: 2444426 | 6320441 | 74627182 | 817821 | NP_010521.1 | NM_001180543.1
GenBank/EMBL/DDBJ: AAB81948.1 | CAA89721.1 | DAA12076.1 | AF020682 | Z49701
Amino Acid Sequence (or in FASTA format)
       1  MDKYTALIHD ENFSTLTLNV SRYPKSLAYW EKLLNYIVKA SAPICKSTEP
      51  QLLKLIRCTY SSMLNEFPYL ENYYIDFALL EYKLGNVSMS HKIFQRGLQA
     101  FNQRSLLLWT SYLKFCNNVI SHQKQLFKKY ETAEEYVGLH FFSGEFWDLY
     151  LEQISSRCTS SKKYWNVLRK ILEIPLHSFS KFYALWLQRI DDIMDLKQLS
     201  QLTSKDELLK KLKIDINYSG RKGPYLQDAK KKLKKITKEM YMVVQYQVLE
     251  IYSIFESKIY INYYTSPETL VSSDEIETWI KYLDYTITLQ TDSLTHLNFQ
     301  RALLPLAHYD LVWIKYSKWL INSKNDLLGA KNVLLMGLKF SLKKTEIIKL
     351  LYSVICKLNE YVLLRNLLEK IESSYSDNVE NVDDFEIFWD YLQFKTFCQN
     401  SLYSSRYSDS QSNGLLNKEL FDKVWKRLSC KEKKSGQEIL LNNLVQFYSK
     451  DTVEFVEKNI FQKIIEFGWE YYLQNGMFWN CYCRLIYFDT SRSYLDKRQY
     501  IVRKIWPQID KKFAQSVLPS LTEFCESYFP EEMDTLEEMF TEEP*     

external links for Prp42p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) CYC2008 (complexes) MIPS YeastGFP
YGOB Complexome Pfam domains YeastRC Public Image Repository
YOGY DIP YeastRC Structure Prediction (Seattle)

GeneMANIA


IMP


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Prp42p
1) Gottschalk A, et al.  (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93
2) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41