HTA1/YDR225W Protein Information Help

Standard Name Hta1p
Systematic Name Ydr225wp
Alias H2a1p 1 , Spt11p 2
ORF Classification Verified
Description Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of two nearly identical subtypes (see also HTA2); DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p (1, 3, 4, 5, 6)
Name Description Histone h Two A 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 132
Molecular Weight (Da) 13,989
Isoelectric Point (pI) 11.43

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Hta1p (InterPro)
Physical Interactions There are 256 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052DD9 | P04911
MIPS: YDR225W
NCBI: 121967 | 15988134 | 15988138 | 171031 | 3751 | 375332468 | 375332470 | 398366187 | 532749 | 728681 | NP_010511.3
GenBank/EMBL/DDBJ: DAA12067.1 | M18455 | U13239 | V01304 | Z48612
Amino Acid Sequence (or in FASTA format)
 
       1  MSGGKGGKAG SAAKASQSRS AKAGLTFPVG RVHRLLRRGN YAQRIGSGAP
      51  VYLTAVLEYL AAEILELAGN AARDNKKTRI IPRHLQLAIR NDDELNKLLG
     101  NVTIAQGGVL PNIHQNLLPK KSAKATKASQ EL*

external links for Hta1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA


YeastRC Mass Spec (Seattle)


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Hta1p
1) Choe J, et al.  (1982) The two yeast histone H2A genes encode similar protein subtypes. Proc Natl Acad Sci U S A 79(5):1484-7
2) Sherwood PW and Osley MA  (1991) Histone regulatory (hir) mutations suppress delta insertion alleles in Saccharomyces cerevisiae. Genetics 128(4):729-38
3) Norris D, et al.  (1988) The effect of histone gene deletions on chromatin structure in Saccharomyces cerevisiae. Science 242(4879):759-61
4) Downs JA, et al.  (2000) A role for Saccharomyces cerevisiae histone H2A in DNA repair. Nature 408(6815):1001-4
5) Meeks-Wagner D and Hartwell LH  (1986) Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission. Cell 44(1):43-52
6) Song OK, et al.  (2003) An Nalpha-acetyltransferase responsible for acetylation of the N-terminal residues of histones H4 and H2A. J Biol Chem 278(40):38109-12