SPR28/YDR218C Protein Information

Standard Name	Spr28p
Systematic Name	Ydr218cp
ORF Classification	Verified
Description	Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation (1)
Name Description	SPorulation Regulated 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	423
Molecular Weight (Da)	48,193
Isoelectric Point (pI)	5.76

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Spr28p (InterPro)
Physical Interactions	There are 6 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006C4F5 \| Q04921 MIPS: YDR218C NCBI: 46577334 \| 6320424 \| 728674 \| NP_010504.1 GenBank/EMBL/DDBJ: DAA12061.1 \| Z48612

Amino Acid Sequence (or in FASTA format)
1 MFPMKDHSAL EQHTLSRDEL RRRKGYKKGL QLSILLLGEK GSGKSTFLNN 51 LCGQDISLSD GDYDDDDDKV TNNVTPENGN AIEDIDPGYK TAHLSPGLKL 101 VTRRVYLNDE LGVPITLDII LFPGCGDNVD NSQSSVVIKN YLDQQFANVL 151 KEEVRIKRNT KETDGRPHVC LYFLKSTPRG VKKFDIELMK TICDKVNLIP 201 IIPKADGLTE TELNLHKDIV RQEISQNNIR VFDFKSDTLG ETLALYDMDI 251 DSSSAKSKYD NDTKIKEISP FAIVCSKTFN KNSENRVEHI RTYEWGSLVV 301 EDQNTSDFIY LKAILLGSHL QELKDVTNNV LYENYRAKVL TEKKNNYDIP 351 NYSYIDETSR GSVSNVSTRR NSASRTLGNP DTNDENAYQI HKEIDEKNRI 401 IEDYQRKIDL LEKMLAAPHQ NKV*

Amino Acid Sequence (or in FASTA format)

       1  MFPMKDHSAL EQHTLSRDEL RRRKGYKKGL QLSILLLGEK GSGKSTFLNN
      51  LCGQDISLSD GDYDDDDDKV TNNVTPENGN AIEDIDPGYK TAHLSPGLKL
     101  VTRRVYLNDE LGVPITLDII LFPGCGDNVD NSQSSVVIKN YLDQQFANVL
     151  KEEVRIKRNT KETDGRPHVC LYFLKSTPRG VKKFDIELMK TICDKVNLIP
     201  IIPKADGLTE TELNLHKDIV RQEISQNNIR VFDFKSDTLG ETLALYDMDI
     251  DSSSAKSKYD NDTKIKEISP FAIVCSKTFN KNSENRVEHI RTYEWGSLVV
     301  EDQNTSDFIY LKAILLGSHL QELKDVTNNV LYENYRAKVL TEKKNNYDIP
     351  NYSYIDETSR GSVSNVSTRR NSASRTLGNP DTNDENAYQI HKEIDEKNRI
     401  IEDYQRKIDL LEKMLAAPHQ NKV*

external links for Spr28p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Spr28p

1)	De Virgilio C, et al. (1996) SPR28, a sixth member of the septin gene family in Saccharomyces cerevisiae that is expressed specifically in sporulating cells. Microbiology 142 ( Pt 10):2897-905