TAF10/YDR167W Protein Information

Standard Name	Taf10p 1
Systematic Name	Ydr167wp
Alias	Taf23p 2 , Taf25p 3
ORF Classification	Verified
Description	Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification (1, 4, 5)
Name Description	TATA binding protein-Associated Factor
Gene Product	TafII25

Experimental Data
Molecules/cell	3370 6

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	206
Molecular Weight (Da)	23,019
Isoelectric Point (pI)	4.28

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Taf10p (InterPro)
Physical Interactions	There are 282 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000005312D \| Q12030 MIPS: YDR167W NCBI: 1354326 \| 3024704 \| 398365921 \| 642276 \| NP_010451.3 GenBank/EMBL/DDBJ: DAA12007.1 \| U51636 \| Z47813

Amino Acid Sequence (or in FASTA format)
1 MDFEEDYDAE FDDNQEGQLE TPFPSVAGAD DGDNDNDDSV AENMKKKQKR 51 EAVVDDGSEN AFGIPEFTRK DKTLEEILEM MDSTPPIIPD AVIDYYLTKN 101 GFNVADVRVK RLLALATQKF VSDIAKDAYE YSRIRSSVAV SNANNSQARA 151 RQLLQGQQQP GVQQISQQQH QQNEKTTASK VVLTVNDLSS AVAEYGLNIG 201 RPDFYR*

Amino Acid Sequence (or in FASTA format)

       1  MDFEEDYDAE FDDNQEGQLE TPFPSVAGAD DGDNDNDDSV AENMKKKQKR
      51  EAVVDDGSEN AFGIPEFTRK DKTLEEILEM MDSTPPIIPD AVIDYYLTKN
     101  GFNVADVRVK RLLALATQKF VSDIAKDAYE YSRIRSSVAV SNANNSQARA
     151  RQLLQGQQQP GVQQISQQQH QQNEKTTASK VVLTVNDLSS AVAEYGLNIG
     201  RPDFYR*

external links for Taf10p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Taf10p

1)	Tora L (2002) A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription. Genes Dev 16(6):673-5
2)	Moqtaderi Z, et al. (1996) Yeast homologues of higher eukaryotic TFIID subunits. Proc Natl Acad Sci U S A 93(25):14654-8
3)	Klebanow ER, et al. (1996) Isolation and characterization of TAF25, an essential yeast gene that encodes an RNA polymerase II-specific TATA-binding protein-associated factor. J Biol Chem 271(23):13706-15
4)	Grant PA, et al. (1998) A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation. Cell 94(1):45-53
5)	Lee TI and Young RA (2000) Transcription of eukaryotic protein-coding genes. Annu Rev Genet 34:77-137
6)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41