KIN1/YDR122W Protein Information Help

Standard Name Kin1p 1
Systematic Name Ydr122wp
ORF Classification Verified
Description Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication (1, 2, 3)
Name Description KINase 1
Experimental Data
Molecules/cell 279 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,064
Molecular Weight (Da) 120,070
Isoelectric Point (pI) 9.36

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Kin1p (InterPro)
Physical Interactions There are 52 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000012DE64 | P13185
MIPS: YDR122W
NCBI: 171787 | 2507199 | 6320327 | 747896 | NP_010407.1 | NM_001180430.1
GenBank/EMBL/DDBJ: AAA34722.1 | CAA88675.1 | DAA11968.1 | M69017 | Z48758
External Classifications EC: 2.7.11.1 [Non-specific serine/threonine protein kinase]
Amino Acid Sequence (or in FASTA format)
       1  MDDYHVNTAF SMGRGNQQDD GNSESNSMHT QPSTMAPATL RMMGKSPQQQ
      51  QQQNTPLMPP ADIKYANNGN SHQAEQKERQ VELEGKSREN APKPNTTSQS
     101  RVSSSQGMPK QFHRKSLGDW EFVETVGAGS MGKVKLAKHR YTNEVCAVKI
     151  VNRATKAFLH KEQMLPPPKN EQDVLERQKK LEKEISRDKR TIREASLGQI
     201  LYHPHICRLF EMCTLSNHFY MLFEYVSGGQ LLDYIIQHGS IREHQARKFA
     251  RGIASALIYL HANNIVHRDL KIENIMISDS SEIKIIDFGL SNIYDSRKQL
     301  HTFCGSLYFA APELLKANPY TGPEVDVWSF GVVLFVLVCG KVPFDDENSS
     351  VLHEKIKQGK VEYPQHLSIE VISLLSKMLV VDPKRRATLK QVVEHHWMVR
     401  GFNGPPPSYL PKRVPLTIEM LDINVLKEMY RLEFIDDVEE TRSVLVSIIT
     451  DPTYVLLSRQ YWTLAAKMNA ESSDNGNAPN ITESFEDPTR AYHPMISIYY
     501  LTSEMLDRKH AKIRNQQQRQ SHENIEKLSE IPESVKQRDV EVNTTAMKSE
     551  PEATLATKDT SVPFTPKNSD GTEPPLHVLI PPRLAMPEQA HTSPTSRKSS
     601  DNQRREMEYA LSPTPQGNDY QQFRVPSTTG DPSEKAKFGN IFRKLSQRRK
     651  KTIEQTSVNS NNSINKPVQK THSRAVSDFV PGFAKPSYDS NYTMNEPVKT
     701  NDSRGGNKGD FPALPADAEN MVEKQREKQI EEDIMKLHDI NKQNNEVAKG
     751  SGREAYAAQK FEGSDDDENH PLPPLNVAKG RKLHPSARAK SVGHARRESL
     801  KYMRPPMPSS AYPQQELIDT GFLESSDDNK SDSLGNVTSQ TNDSVSVHSV
     851  NAHINSPSVE KELTDEEILQ EASRAPAGSM PSIDFPRSLF LKGFFSVQTT
     901  SSKPLPIVRY KIMFVLRKMN IEFKEVKGGF VCMQRFSSNN VAAKREGTPR
     951  SIMPLSHHES IRRQGSNKYS PSSPLTTNSI HQRKTSITET YGDDKHSGTS
    1001  LENIHQQGDG SEGMTTTEKE PIKFEIHIVK VRIVGLAGVH FKKISGNTWL
    1051  YKELASSILK ELKL*                                      

external links for Kin1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
YGOB CYC2008 (complexes) MIPS YPL+
YOGY Complexome Pfam domains YeastGFP

DIP YeastRC Structure Prediction (Seattle) YeastRC Public Image Repository

GeneMANIA


IMP


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Kin1p
1) Levin DE, et al.  (1987) Two yeast genes that encode unusual protein kinases. Proc Natl Acad Sci U S A 84(17):6035-9
2) Elbert M, et al.  (2005) The yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machinery. Mol Biol Cell 16(2):532-49
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41