RAD55/YDR076W Protein Information

Standard Name	Rad55p 1
Systematic Name	Ydr076wp
ORF Classification	Verified
Description	Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad57p (2, 3)
Name Description	RADiation sensitive

Experimental Data
Molecules/cell	1050 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	406
Molecular Weight (Da)	46,349
Isoelectric Point (pI)	6.77

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rad55p (InterPro)
Physical Interactions	There are 23 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013303A \| P38953 MIPS: YDR076W NCBI: 1321666 \| 1431541 \| 398365443 \| 509494 \| 51830232 \| 558247 \| 577803 \| 730467 \| NP_010361.3 \| NM_001180384.3 GenBank/EMBL/DDBJ: DAA11922.1 \| AY723773 \| D10481 \| U01144 \| X82086 \| Z46796 \| Z74372

Amino Acid Sequence (or in FASTA format)
1 MSLGIPLSQL IVESPKPLSS GITGLDEILN LGFQARSIYE IFGPPGIGKT 51 NFGIQLVCNS LEGIQQSEIN DDKILWIETF QEMPINILRE RFQKFKIVEE 101 NVKRVRITKF GQLLYFFQNL FKLSQSVRYK LVIIDGFSQL VCDHLCTLSK 151 RGGGMIDKTI HELKCRHLIL IFTVMTKYTH STGSTIIVLN DCMNTAFQSN 201 EFESLEEYYE ILDDGSNFFV NSNNERRKNN VHILKSALVA NIAMGSKDST 251 WEVFLRDRIG LFRDWNEQVD ETVFVKSKRV KASSSQSNEG CTTIKEMRIN 301 KRNFENLRIA IVFNLHGEDR KREGRNLKRS RSSDDRNYIV KFDFDKATGQ 351 LRDIIDLKPD TANIASFPTL STSSSSCSQV FNNIDSNDNP LPNAEGKEEI 401 IYDSEG*

Amino Acid Sequence (or in FASTA format)

       1  MSLGIPLSQL IVESPKPLSS GITGLDEILN LGFQARSIYE IFGPPGIGKT
      51  NFGIQLVCNS LEGIQQSEIN DDKILWIETF QEMPINILRE RFQKFKIVEE
     101  NVKRVRITKF GQLLYFFQNL FKLSQSVRYK LVIIDGFSQL VCDHLCTLSK
     151  RGGGMIDKTI HELKCRHLIL IFTVMTKYTH STGSTIIVLN DCMNTAFQSN
     201  EFESLEEYYE ILDDGSNFFV NSNNERRKNN VHILKSALVA NIAMGSKDST
     251  WEVFLRDRIG LFRDWNEQVD ETVFVKSKRV KASSSQSNEG CTTIKEMRIN
     301  KRNFENLRIA IVFNLHGEDR KREGRNLKRS RSSDDRNYIV KFDFDKATGQ
     351  LRDIIDLKPD TANIASFPTL STSSSSCSQV FNNIDSNDNP LPNAEGKEEI
     401  IYDSEG*

external links for Rad55p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Rad55p

1)	Kuwahara, S. et al. (1996) Cloning of the RAD55 gene and identification of its gene product in Saccharomyces cerevisiae Unpublished
2)	Fortin GS and Symington LS (2002) Mutations in yeast Rad51 that partially bypass the requirement for Rad55 and Rad57 in DNA repair by increasing the stability of Rad51-DNA complexes. EMBO J 21(12):3160-70
3)	Symington LS (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev 66(4):630-70, table of contents
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41