PHO13/YDL236W Protein Information

Standard Name	Pho13p
Systematic Name	Ydl236wp
ORF Classification	Verified
Description	Alkaline phosphatase specific for p-nitrophenyl phosphate; also has protein phosphatase activity (1, 2)
Name Description	PHOsphate metabolism

Experimental Data
Molecules/cell	2980 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	312
Molecular Weight (Da)	34,624
Isoelectric Point (pI)	6.3

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Pho13p (InterPro)
Physical Interactions	There are 15 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006B3EB \| P19881 MIPS: YDL236W NCBI: 1431400 \| 56757590 \| 5924022 \| 6319965 \| NP_010045.1 GenBank/EMBL/DDBJ: DAA11630.1 \| X51611 \| Z74284
External Classifications	EC: 3.1.3.41 [4-nitrophenylphosphatase]

Amino Acid Sequence (or in FASTA format)
1 MTAQQGVPIK ITNKEIAQEF LDKYDTFLFD CDGVLWLGSQ ALPYTLEILN 51 LLKQLGKQLI FVTNNSTKSR LAYTKKFASF GIDVKEEQIF TSGYASAVYI 101 RDFLKLQPGK DKVWVFGESG IGEELKLMGY ESLGGADSRL DTPFDAAKSP 151 FLVNGLDKDV SCVIAGLDTK VNYHRLAVTL QYLQKDSVHF VGTNVDSTFP 201 QKGYTFPGAG SMIESLAFSS NRRPSYCGKP NQNMLNSIIS AFNLDRSKCC 251 MVGDRLNTDM KFGVEGGLGG TLLVLSGIET EERALKISHD YPRPKFYIDK 301 LGDIYTLTNN EL*

Amino Acid Sequence (or in FASTA format)

       1  MTAQQGVPIK ITNKEIAQEF LDKYDTFLFD CDGVLWLGSQ ALPYTLEILN
      51  LLKQLGKQLI FVTNNSTKSR LAYTKKFASF GIDVKEEQIF TSGYASAVYI
     101  RDFLKLQPGK DKVWVFGESG IGEELKLMGY ESLGGADSRL DTPFDAAKSP
     151  FLVNGLDKDV SCVIAGLDTK VNYHRLAVTL QYLQKDSVHF VGTNVDSTFP
     201  QKGYTFPGAG SMIESLAFSS NRRPSYCGKP NQNMLNSIIS AFNLDRSKCC
     251  MVGDRLNTDM KFGVEGGLGG TLLVLSGIET EERALKISHD YPRPKFYIDK
     301  LGDIYTLTNN EL*

external links for Pho13p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Pho13p

1)	Tuleva B, et al. (1998) A specific alkaline phosphatase from Saccharomyces cerevisiae with protein phosphatase activity. FEMS Microbiol Lett 161(1):139-44
2)	Kaneko Y, et al. (1989) Molecular characterization of a specific p-nitrophenylphosphatase gene, PHO13, and its mapping by chromosome fragmentation in Saccharomyces cerevisiae. Mol Gen Genet 220(1):133-9
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41