GYP7/YDL234C Protein Information Help

Standard Name Gyp7p 1
Systematic Name Ydl234cp
ORF Classification Verified
Description GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking (1, 2, 3)
Name Description Gtpase-activating protein for Ypt7 Protein 1
Experimental Data
Molecules/cell 2460 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 746
Molecular Weight (Da) 87,305
Isoelectric Point (pI) 4.88

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Gyp7p (InterPro)
Physical Interactions There are 3 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000012BE79 | P48365
MIPS: YDL234C
NCBI: 1064935 | 1346228 | 1431396 | 1903295 | 6319967 | NP_010047.1
GenBank/EMBL/DDBJ: DAA11632.1 | X79552 | Z74281 | Z74282
Amino Acid Sequence (or in FASTA format)
 
       1  MSKILFCKSK VFLHPTSDAR DNIAGFLLLT LEANKLSHQA ILQYIPESGL
      51  STLEISKLLK HEAKVGTCPT STPFVIENSI NFSNLVNTSL GQAFEISLSQ
     101  IYCIQFRPPS PNGWYVGSLV IYPLTEQFTG FQPPVLFFHD QLCPSTTDKL
     151  KRLRKSMNPF DDSDELYWGG VDLRNKINEL MELKKSNLEP EFWLVNPSLN
     201  DLRNFVSKDL LESYNNSKKD TTELATAGVK LNEKFQEWKW NVMSKIADVT
     251  TKSTNFIDSW LTNNSPIQKS QIDNEYLQKL LNNEKVKQIE QDYDSARVYL
     301  ANWSLGVKQE AERYQKQNKL FDSYRNNIFN DLNLTDELSD TEINNALQRQ
     351  FPLTEAKWNS LWDENDGRLR VTVNEVKDFI FHGGLENDSL RGKVWGFLLE
     401  IYPWDSSQDE RVQIDQTLAA EYDQLKLTWS KDFLQFDDED EEEYWNDQLF
     451  RISKDVRRCD RNLEIFQYNT IDGLPPPPQQ LPANENNSTS PESANDESDD
     501  ADDGVRNPHL IHLQNILITY NVYNTNLGYV QGMTDLLSPI YVIMKEEWKT
     551  FWCFTHFMDI MERNFLRDQS GIHEQMLTLV ELVQLMLPEL SEHLNKCDSG
     601  NLFFCFRMLL VWFKREFEME DIMHIWENFW TFYYSSQFQL FFMLAILQKN
     651  SQAILQHLNQ FDQILKFFNE LNGKLDWNDL MVRAELLFKK FEKMMHVMER
     701  DLQNVSSSSS SSSTGVLPCQ SERLTLLLSK KPIIRHEGQR SKNSVK*

external links for Gyp7p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Gyp7p
1) Vollmer P, et al.  (1999) Primary structure and biochemical characterization of yeast GTPase-activating proteins with substrate preference for the transport GTPase Ypt7p. Eur J Biochem 260(1):284-90
2) Eitzen G, et al.  (2000) Sequential action of two GTPases to promote vacuole docking and fusion. EMBO J 19(24):6713-20
3) Eitzen G, et al.  (2001) Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking. EMBO J 20(20):5650-6
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41