NHP2/YDL208W Protein Information Help

Standard Name Nhp2p 1
Systematic Name Ydl208wp
ORF Classification Verified
Description Nuclear protein related to mammalian high mobility group (HMG) proteins, essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing (1, 2)
Name Description Non-Histone Protein 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 156
Molecular Weight (Da) 17,122
Isoelectric Point (pI) 10.52

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Nhp2p (InterPro)
Physical Interactions There are 97 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001772F0 | P32495
MIPS: YDL208W
NCBI: 1429348 | 1431346 | 339717346 | 339717347 | 59799862 | 666101 | 82795243 | NP_010073.2
GenBank/EMBL/DDBJ: DAA11656.1 | X57714 | X99000 | Z74256
Amino Acid Sequence (or in FASTA format)
 
       1  MGKDNKEHKE SKESKTVDNY EARMPAVLPF AKPLASKKLN KKVLKTVKKA
      51  SKAKNVKRGV KEVVKALRKG EKGLVVIAGD ISPADVISHI PVLCEDHSVP
     101  YIFIPSKQDL GAAGATKRPT SVVFIVPGSN KKKDGKNKEE EYKESFNEVV
     151  KEVQAL*

external links for Nhp2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) BioPIXIE MIPS YeastGFP
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome

YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Nhp2p
1) Kolodrubetz D and Burgum A  (1991) Sequence and genetic analysis of NHP2: a moderately abundant high mobility group-like nuclear protein with an essential function in Saccharomyces cerevisiae. Yeast 7(2):79-90
2) Henras A, et al.  (1998) Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs. EMBO J 17(23):7078-90