ARF1/YDL192W Protein Information

Standard Name	Arf1p 1
Systematic Name	Ydl192wp
ORF Classification	Verified
Description	ADP-ribosylation factor; GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; ARF1 has a paralog, ARF2, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description	ADP-Ribosylation Factor 1

Experimental Data
Molecules/cell	19300 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	181
Molecular Weight (Da)	20,529
Isoelectric Point (pI)	7.46

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Arf1p (InterPro)
Physical Interactions	There are 124 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001682D3 \| P11076 MIPS: YDL192W NCBI: 1004303 \| 114121 \| 1431314 \| 171073 \| 222142955 \| 300193097 \| 377656314 \| 377656317 \| 6320009 \| NP_010089.1 GenBank/EMBL/DDBJ: DAA11671.1 \| J03276 \| X83276 \| Z74240

Amino Acid Sequence (or in FASTA format)
1 MGLFASKLFS NLFGNKEMRI LMVGLDGAGK TTVLYKLKLG EVITTIPTIG 51 FNVETVQYKN ISFTVWDVGG QDRIRSLWRH YYRNTEGVIF VVDSNDRSRI 101 GEAREVMQRM LNEDELRNAA WLVFANKQDL PEAMSAAEIT EKLGLHSIRN 151 RPWFIQATCA TSGEGLYEGL EWLSNSLKNS T*

Amino Acid Sequence (or in FASTA format)

       1  MGLFASKLFS NLFGNKEMRI LMVGLDGAGK TTVLYKLKLG EVITTIPTIG
      51  FNVETVQYKN ISFTVWDVGG QDRIRSLWRH YYRNTEGVIF VVDSNDRSRI
     101  GEAREVMQRM LNEDELRNAA WLVFANKQDL PEAMSAAEIT EKLGLHSIRN
     151  RPWFIQATCA TSGEGLYEGL EWLSNSLKNS T*

external links for Arf1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Mass Spec (Seattle)

References cited on this page View Complete Literature Guide for Arf1p

1)	Sewell JL and Kahn RA (1988) Sequences of the bovine and yeast ADP-ribosylation factor and comparison to other GTP-binding proteins. Proc Natl Acad Sci U S A 85(13):4620-4
2)	Stearns T, et al. (1990) ADP-ribosylation factor is functionally and physically associated with the Golgi complex. Proc Natl Acad Sci U S A 87(3):1238-42
3)	Stearns T, et al. (1990) ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes. Mol Cell Biol 10(12):6690-9
4)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41