INH1/YDL181W Protein Information 
| Standard Name | Inh1p 1 |
|---|---|
| Systematic Name | Ydl181wp |
| ORF Classification | Verified |
| Description | Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase; inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has a calmodulin-binding motif and binds calmodulin in vitro; INH1 has a paralog, STF1, that arose from the whole genome duplication (2, 3, 4) |
| Name Description | INHibitor (of F1F0-ATPase) 1 |
| Experimental Data | |
|---|---|
| Molecules/cell | 981 5 |
| Click on image for expanded interactive view |
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| Post-translational Modifications | PhosphoGRID | PhosphoPep Database |
|---|---|
| Domains/motifs | See the graphical view and list of proteins that share domains/motifs in common with Inh1p (InterPro) |
| Physical Interactions | There are 24 total physical interactions (BioGRID) |
| Homologs | PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer |
| External Sequence Databases |
EBI: UPI000012D0D6 | P01097 MIPS: YDL181W NCBI: 1004313 | 124015 | 1431293 | 218435 | 449802279 | 449802289 | 45270638 | 6320020 | NP_010100.1 GenBank/EMBL/DDBJ: DAA11681.1 | AY558374 | D00443 | X83276 | Z74229 |
external links for Inh1p
| Homologs | Interaction Resources | Protein databases/Other | Localization Resources |
|---|---|---|---|
| BLASTP (NCBI) | BioGRID | SCOP Superfamily | Organelle DB |
| Ashbya (AGD) | BOND | GPMdb (Mass Spec.) | YPL+ |
| YGOB | BioPIXIE | MIPS | YeastGFP |
| YOGY | CYC2008 (complexes) | Pfam domains | YeastRC Public Image Repository |
| Complexome | YeastRC Structure Prediction (Seattle) | ||
| DIP | |||
| GeneMANIA |
References cited on this page View Complete Literature Guide for Inh1p
| 1) | Ichikawa N, et al. (1990) Activation of ATP hydrolysis by an uncoupler in mutant mitochondria lacking an intrinsic ATPase inhibitor in yeast. J Biol Chem 265(11):6274-8 |
| 2) | Dienhart M, et al. (2002) Formation of the yeast F1F0-ATP synthase dimeric complex does not require the ATPase inhibitor protein, Inh1. J Biol Chem 277(42):39289-95 |
| 3) | Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 |
| 4) | Contessi S, et al. (2005) Identification of a conserved calmodulin-binding motif in the sequence of F0F1 ATPsynthase inhibitor protein. J Bioenerg Biomembr 37(5):317-26 |
| 5) | Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41 |
