YDL144C Protein Information

Systematic Name	Ydl144cp
ORF Classification	Verified
Description	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL144C is not an essential gene; protein abundance increases in response to DNA replication stress (1, 2, 3)

Experimental Data
Molecules/cell	5170 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	356
Molecular Weight (Da)	39,782
Isoelectric Point (pI)	6.72

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ydl144cp (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 9 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001D476D \| Q07589 MIPS: YDL144C NCBI: 1431225 \| 37362628 \| 84027744 \| NP_010137.2 GenBank/EMBL/DDBJ: DAA11714.1 \| Z74192

Amino Acid Sequence (or in FASTA format)
1 MSRILVIGAG GVGVITALSL WLKKESDVSL VVRSDYDRVL KHGYTIESCD 51 YGRLEGWRPH HIYSSVEDAA SAADNQGYNY IVVTTKNIID GPVNSRVSNI 101 IRPVLEKNKE LHGPQLTTHI LLVQNGIDIE KEIWAEFPRE QYRYTVLSGI 151 QLIGSTKIGS GHISQVGQDH LSCGAFDPQD AAAIQAANDF VRMYSNEGQN 201 FVEFDPRVRY SRWKKLLYNA AINTSTALVG LDVPRCLEFG VNKKSTEIEV 251 FHPAMREIIA IAASEGIIIE EEFITMFTEI TRKKVFKPSM CVDCEKGQLM 301 ELEVILGNPI RIAKRNGVAT PTLSILYNLL VLVQAKLKER KGLLKFDEKT 351 ATLVDE*

Amino Acid Sequence (or in FASTA format)

       1  MSRILVIGAG GVGVITALSL WLKKESDVSL VVRSDYDRVL KHGYTIESCD
      51  YGRLEGWRPH HIYSSVEDAA SAADNQGYNY IVVTTKNIID GPVNSRVSNI
     101  IRPVLEKNKE LHGPQLTTHI LLVQNGIDIE KEIWAEFPRE QYRYTVLSGI
     151  QLIGSTKIGS GHISQVGQDH LSCGAFDPQD AAAIQAANDF VRMYSNEGQN
     201  FVEFDPRVRY SRWKKLLYNA AINTSTALVG LDVPRCLEFG VNKKSTEIEV
     251  FHPAMREIIA IAASEGIIIE EEFITMFTEI TRKKVFKPSM CVDCEKGQLM
     301  ELEVILGNPI RIAKRNGVAT PTLSILYNLL VLVQAKLKER KGLLKFDEKT
     351  ATLVDE*

external links for Ydl144cp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Ydl144cp

1)	Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
2)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3)	Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41