ARF2/YDL137W Protein Information

Standard Name	Arf2p 1
Systematic Name	Ydl137wp
ORF Classification	Verified
Description	ADP-ribosylation factor; GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; ARF2 has a paralog, ARF1, that arose from the whole genome duplication (1, 2, 3)
Name Description	ADP-Ribosylation Factor 1

Experimental Data
Molecules/cell	25000 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	181
Molecular Weight (Da)	20,657
Isoelectric Point (pI)	7.46

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Arf2p (InterPro)
Physical Interactions	There are 24 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001126C0 \| P19146 MIPS: YDL137W NCBI: 114124 \| 124263226 \| 1419224 \| 1431211 \| 171071 \| 27065721 \| 51013511 \| 6320064 \| NP_010144.1 GenBank/EMBL/DDBJ: DAA11721.1 \| AY693030 \| EF123146 \| M35158 \| X96876 \| Z74185

Amino Acid Sequence (or in FASTA format)
1 MGLYASKLFS NLFGNKEMRI LMVGLDGAGK TTVLYKLKLG EVITTIPTIG 51 FNVETVQYKN ISFTVWDVGG QDRIRSLWRH YYRNTEGVIF VIDSNDRSRI 101 GEAREVMQRM LNEDELRNAV WLVFANKQDL PEAMSAAEIT EKLGLHSIRN 151 RPWFIQSTCA TSGEGLYEGL EWLSNNLKNQ S*

Amino Acid Sequence (or in FASTA format)

       1  MGLYASKLFS NLFGNKEMRI LMVGLDGAGK TTVLYKLKLG EVITTIPTIG
      51  FNVETVQYKN ISFTVWDVGG QDRIRSLWRH YYRNTEGVIF VIDSNDRSRI
     101  GEAREVMQRM LNEDELRNAV WLVFANKQDL PEAMSAAEIT EKLGLHSIRN
     151  RPWFIQSTCA TSGEGLYEGL EWLSNNLKNQ S*

external links for Arf2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Arf2p

1)	Stearns T, et al. (1990) ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes. Mol Cell Biol 10(12):6690-9
2)	Poon PP, et al. (1999) Retrograde transport from the yeast Golgi is mediated by two ARF GAP proteins with overlapping function. EMBO J 18(3):555-64
3)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41