SRP14/YDL092W Protein Information Help

Standard Name Srp14p
Systematic Name Ydl092wp
ORF Classification Verified
Description Signal recognition particle (SRP) subunit, interacts with the RNA component of SRP to form the Alu domain, which is the region of SRP responsible for arrest of nascent chain elongation during membrane targeting; homolog of mammalian SRP14 (1, 2, 3)
Name Description Signal Recognition Particle
Experimental Data
Molecules/cell 8000 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 146
Molecular Weight (Da) 16,430
Isoelectric Point (pI) 10.51

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Srp14p (InterPro)
Physical Interactions There are 45 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052E7C | P38985
MIPS: YDL092W
NCBI: 1199555 | 1431124 | 1903284 | 45270208 | 531014 | 6320111 | 730823 | NP_010191.1
GenBank/EMBL/DDBJ: DAA11766.1 | AY558159 | L35155 | X95644 | Z74139 | Z74140
Amino Acid Sequence (or in FASTA format)
 
       1  MANTGCLSPG AFLSKVPEFF QTANEKHITV RLTAKRLIEH DPVEGNLEFD
      51  STNHPDYDVS KKASEISVSS RSDREYPLLI RMSYGSHDKK TKCSTVVKAS
     101  ELDQFWQEYS SVFKGGMQNL IKKKKKKSKN GTISKTGKKN KVAKKN*

external links for Srp14p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains YeastRC Public Image Repository

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Srp14p
1) Strub K, et al.  (1999) The Alu domain homolog of the yeast signal recognition particle consists of an Srp14p homodimer and a yeast-specific RNA structure. RNA 5(10):1333-47
2) Mason N, et al.  (2000) Elongation arrest is a physiologically important function of signal recognition particle. EMBO J 19(15):4164-74
3) Brown JD, et al.  (1994) Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression. EMBO J 13(18):4390-400
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41