MDH3/YDL078C Protein Information

Standard Name	Mdh3p
Systematic Name	Ydl078cp
ORF Classification	Verified
Description	Peroxisomal malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle (1)
Name Description	Malate DeHydrogenase

Experimental Data
Molecules/cell	3300 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	343
Molecular Weight (Da)	37,186
Isoelectric Point (pI)	10

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mdh3p (InterPro)
Physical Interactions	There are 27 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001682DD \| P32419 MIPS: YDL078C NCBI: 1431096 \| 171918 \| 2506850 \| 6320125 \| NP_010205.1 GenBank/EMBL/DDBJ: DAA11781.1 \| M98763 \| Z74126
External Classifications	EC: 1.1.1.37 [Malate dehydrogenase]

Amino Acid Sequence (or in FASTA format)
1 MVKVAILGAS GGVGQPLSLL LKLSPYVSEL ALYDIRAAEG IGKDLSHINT 51 NSSCVGYDKD SIENTLSNAQ VVLIPAGVPR KPGLTRDDLF KMNAGIVKSL 101 VTAVGKFAPN ARILVISNPV NSLVPIAVET LKKMGKFKPG NVMGVTNLDL 151 VRAETFLVDY LMLKNPKIGQ EQDKTTMHRK VTVIGGHSGE TIIPIITDKS 201 LVFQLDKQYE HFIHRVQFGG DEIVKAKQGA GSATLSMAFA GAKFAEEVLR 251 SFHNEKPETE SLSAFVYLPG LKNGKKAQQL VGDNSIEYFS LPIVLRNGSV 301 VSIDTSVLEK LSPREEQLVN TAVKELRKNI EKGKSFILDS SKL*

Amino Acid Sequence (or in FASTA format)

       1  MVKVAILGAS GGVGQPLSLL LKLSPYVSEL ALYDIRAAEG IGKDLSHINT
      51  NSSCVGYDKD SIENTLSNAQ VVLIPAGVPR KPGLTRDDLF KMNAGIVKSL
     101  VTAVGKFAPN ARILVISNPV NSLVPIAVET LKKMGKFKPG NVMGVTNLDL
     151  VRAETFLVDY LMLKNPKIGQ EQDKTTMHRK VTVIGGHSGE TIIPIITDKS
     201  LVFQLDKQYE HFIHRVQFGG DEIVKAKQGA GSATLSMAFA GAKFAEEVLR
     251  SFHNEKPETE SLSAFVYLPG LKNGKKAQQL VGDNSIEYFS LPIVLRNGSV
     301  VSIDTSVLEK LSPREEQLVN TAVKELRKNI EKGKSFILDS SKL*

external links for Mdh3p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Mdh3p

1)	Steffan JS and McAlister-Henn L (1992) Isolation and characterization of the yeast gene encoding the MDH3 isozyme of malate dehydrogenase. J Biol Chem 267(34):24708-15
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41