RPL31A/YDL075W Protein Information Help

Standard Name Rpl31ap
Systematic Name Ydl075wp
Alias Rpl34p
ORF Classification Verified
Description Ribosomal 60S subunit protein L31A; associates with karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality; homologous to mammalian ribosomal protein L31, no bacterial homolog; RPL31A has a paralog, RPL31B, that arose from the whole genome duplication (1, 2, 3, 4, 5, 6)
Name Description Ribosomal Protein of the Large subunit
Gene Product L31A 2 , L31e 6 , L34A 2 , YL28 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 113
Molecular Weight (Da) 12,953
Isoelectric Point (pI) 10.8

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rpl31ap (InterPro)
Physical Interactions There are 100 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000004F8EA | P0C2H8
MIPS: YDL075W
NCBI: 134034935 | 1431090 | 270346350 | 270346365 | 4390 | 49258862 | 6320128 | NP_010208.1
GenBank/EMBL/DDBJ: DAA11784.1 | X01441 | Z74123
Amino Acid Sequence (or in FASTA format)
 
       1  MAGLKDVVTR EYTINLHKRL HGVSFKKRAP RAVKEIKKFA KLHMGTDDVR
      51  LAPELNQAIW KRGVKGVEYR LRLRISRKRN EEEDAKNPLF SYVEPVLVAS
     101  AKGLQTVVVE EDA*

external links for Rpl31ap
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) BioPIXIE MIPS YeastGFP
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rpl31ap
1) Rosenblum JS, et al.  (1997) A nuclear import pathway for a protein involved in tRNA maturation. J Cell Biol 139(7):1655-61
2) Planta RJ and Mager WH  (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7
3) Lecompte O, et al.  (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Peisker K, et al.  (2008) Ribosome-associated complex binds to ribosomes in close proximity of Rpl31 at the exit of the polypeptide tunnel in yeast. Mol Biol Cell 19(12):5279-88
6) Jenner L, et al.  (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol 22(6):759-67